Risk factors for the development of Clostridium difficile colitis in a surgical ward

Min Jeong Kim; Byung Seup Kim; Jae Woo Kwon; So-Eun Ahn; Seung Soon Lee; Hyoung Chul Park; Bong Hwa Lee

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저자정보: Min Jeong Kim (한림대학교) Byung Seup Kim (중앙대학교) Jae Woo Kwon (한림대학교) So-Eun Ahn (한림대학교) Seung Soon Lee (한림대학교) Hyoung Chul Park (한림대학교) Bong Hwa Lee (한림대학교)

저널정보: 대한외과학회 Annals of Surgical Treatment and Research 대한외과학회지 Vol.83 No.1

발행연도: 2012.7

수록면: 14 - 20 (7page)

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Purpose: Clostridium difficile colitis (CDC) is a nosocomial infection. We attempted to discover the risk factors for the development of CDC in patients admitted to our surgical ward. Methods: We conducted a retrospective chart review of all patients admitted to our surgical ward between January 2010 and July 2011. CDC was confirmed when toxin A/B or toxin B polymerase chain reaction was detected in the stool and clinical symptoms, such as diarrhea, were present. We divided patients into the CDC and non-CDC groups, and compared the clinical features between the two groups. Results: The rate of CDC occurrence was 0.4% (19/4,720 patients). Univariate analysis showed that colectomy (P ＜ 0.001), hospital stays longer than 10 days (P ＜ 0.001), aged over 55 years (P ＜ 0.001) and transfer from medical ward (P = 0.009) were significant parameters for CDC. Multivariate analysis showed that colectomy (P ＜ 0.001; odds ratio [OR], 8.405; 95% confidence interval [CI], 2.927 to 24.132) and hospital stays longer than 10 days (P = 0.035; OR, 10.253; 95% CI, 1.176 to 89.392) were high risk factors for CDC occurrence in the surgical ward. Conclusion: The risk factors for CDC in a surgical ward could be colectomy and a long duration of hospitalization. Therefore, clinicians should consider the possibility of CDC when patients undergo colectomy, are admitted for a long time, and have postoperative diarrhea.

#Clostridium difficile #Colitis #Risk factors #Colectomy

참고문헌 (27)

참고문헌 신청

1. [단행본] - Kulaylat MN / 2008 / Surgical complication, In Sabiston textbook of surgery: the biological basis of modern surgical practice. 18th ed / Saunders : 358 ~ 359

2. [학술지(정기간행물)] - Kelly CP / 1994 / Clostridium difficile colitis / N Engl J Med 330 : 257 ~ 262

3. [학술지(정기간행물)] - McDonald LC / 2006 / Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003 / Emerg Infect Dis 12 : 409 ~ 415

4. [학술지(정기간행물)] - 박혜선 / 2010 / Clostridium difficile 감염은 증가하는가? / 대한소화기학회지 55 (3) : 208 ~ 210

5. [학술지(정기간행물)] - 이윤정 / 2010 / 최근 10년간 Clostridium difficile 대장염의 임상 양상 변화 / 대한소화기학회지 55 (3) : 169 ~ 174

이 논문의 저자 정보

Min-Jeong Kim

소속기관 Kyung Hee University

주요연구분야 공학 > 기계공학 > 기계공학 일반 공학 > 컴퓨터학

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소속기관 한림대학교