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논문 기본 정보

자료유형
학술저널
저자정보
(영산대학교)
저널정보
한국식품영양과학회 한국식품영양과학회지 한국식품영양과학회지 제41권 제8호
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1,072 - 1,078 (7page)

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초록· 키워드

The potential antioxidant and anti-inflammatory effect of water and ethanol extracts from Flammulina velutipes (Curtis) Singer (FVS) on hydrogen peroxide (H2O2) and LPS-induced oxidative damage in PC-12 and RAW264.7 cells were investigated. The DPPH radical scavenging activities of the water extract from FVS was the highest, and the 50% inhibitory concentration value was 0.388 mg/mL. Also, the antioxidant activities of water and ethanol extracts were determined by ferric reducing antioxidant power, 2,2"-azino-bis-(3-ethybenzothiazoline-6-sulphonic acid) radical scavenging activity. In addition, water extract from FVS showed a strongly inhibitory effect on lipid peroxidation by measuring ferric thiocyanate values. The water extract decreased cell apoptosis in PC-12 cells against H2O2-induced oxidative damage. In addition, FVS extracts exhibited the strongest nitric oxide (NO) inhibition activity. It was also found that FVS extract inhibited LPS-induced iNOS and COX-2 expression in RAW264.7 cells. The findings of the present study suggest that extracts of FVS exhibit anti-oxidative and anti-inflammatory activity against oxidative stress and/or stimulated cells.
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목차

  1. Abstract
  2. 서론
  3. 재료 및 방법
  4. 결과 및 고찰
  5. 요약
  6. 감사의 글
  7. 문헌

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UCI(KEPA) : I410-ECN-0101-2013-511-003438850