지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.9
- 수록면
- 146 - 151 (6page)
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초록· 키워드
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Backgrounds/Aims: To find independent predictors that affect the survival in patients with hepatic metastasis of colorectal cancer after surgery and to devise a risk scoring system. Methods: Among 150 patients who underwent hepatic resection after diagnosis of colorectal cancer with hepatic metastasis between March 1994 and February 2009, we analyzed clinical, pathologic and outcome data retrospectively. Results: The 1-year survival rate was 83%, and the 5-year survival rate was 35%. Nine factors were found to be independent predictors of adverse outcome by univariate analysis: stage of primary tumor, CA19-9 ＞36 U/ml, extrahepatic disease, distribution of the hepatic tumor, number of hepatic tumors ＞3, largest hepatic tumor ＞5 cm, total size ＞10 cm, CEA ＞10 ng/ml, and metachronous cancer. The last two of these criteria were also significant risk factors on multivariate analysis. When these criteria were used as a risk scoring system, assigning one point for each criterion and dividing the cases into A, B and C groups, the total score was highly predictive of outcomes (p＜0.001). No patients in group C (6 to 9 points) were long-term survivors. Conclusions: Long-term outcome can be predicted from nine criteria that are readily available for all patients. Patients meeting up to two criteria (group A) are more likely to have a favorable outcome compared to the three or over (groups B and C). This scoring system may offer an easy, rapid, and reliable prognostic indicator of survival outcome after hepatic resection in patients with hepatic metastasis from colorectal cancer. (Korean J Hepatobiliary Pancreat Surg 2011;15:146-151)
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (21)
참고문헌 신청
1. [학술지(정기간행물)] - 이우경 / 2010 / 결장 직장암에 의한 간 전이의 수술적 절제술의 효과 / Journal of the Korean Society of Coloproctolgy 26 (3) : 204 ~ 210
2. [학술지(정기간행물)] - 최평화 / 2008 / 다발성 간전이가 있는 대장암에서 간절제 후 성적 및 재발양상 / Journal of the Korean Society of Coloproctolgy 24 (2) : 100 ~ 106
3. [학술지(정기간행물)] - Scheele J / 1990 / Hepatic metastases from colorectal carcinoma: impact of surgical resection on the natural history / Br J Surg 77 : 1241 ~ 1246
4. [학술지(정기간행물)] - Finlay IG / 1986 / Occult hepatic metastases in colorectal carcinoma / Br J Surg 73 : 732 ~ 735
5. [학술지(정기간행물)] - Li Destri G / 2006 / Colorectal cancer follow-up: useful or useless / Surg Oncol 15 : 1 ~ 12
2. [학술지(정기간행물)] - 최평화 / 2008 / 다발성 간전이가 있는 대장암에서 간절제 후 성적 및 재발양상 / Journal of the Korean Society of Coloproctolgy 24 (2) : 100 ~ 106
3. [학술지(정기간행물)] - Scheele J / 1990 / Hepatic metastases from colorectal carcinoma: impact of surgical resection on the natural history / Br J Surg 77 : 1241 ~ 1246
4. [학술지(정기간행물)] - Finlay IG / 1986 / Occult hepatic metastases in colorectal carcinoma / Br J Surg 73 : 732 ~ 735
5. [학술지(정기간행물)] - Li Destri G / 2006 / Colorectal cancer follow-up: useful or useless / Surg Oncol 15 : 1 ~ 12
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UCI(KEPA) : I410-ECN-0101-2014-514-001274357