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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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초록· 키워드
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Objectives: This study aimed to evaluate the effect of purgation therapy with Natrii sulfas, an oriental medical therapy for stroke patients with constipation, on physiological indexes and the brain edema of rats.
Methods: Brain edema was induced by the middle cerebral artery occlusion (MCAO); Natrii sulfas was administered once after the MCAO. At 3, 6, 15, 24, 48 hours after reperfusion, physiological indexes such as fecal weight, urine volume and water content in stool were assessed, and at 48 hours after reperfusion the edema index was measured.
Results:
1. Purgation therapy with Natrii sulfas significantly improved the reduction of fecal weight caused by ischemic insult (P<0.05).
2. Purgation therapy with Natrii sulfas significantly improved the reduction of urine volume caused by ischemic insult (P<0.05).
3. Purgation therapy with Natrii sulfas significantly improved the reduction of water content in stool caused by ischemic insult (P<0.05).
4. Purgation therapy with Natrii sulfas did not improve the neurological symptom caused by ischemic insult.
5. Purgation therapy with Natrii sulfas did not attenuate the total infarct volume caused by ischemic insult.
6. Purgation therapy with Natrii sulfas attenuated the brain edema caused by ischemic insult (P<0.05).
Conclusions: These results suggest that purgation therapy with Natrii sulfas improves some important symptoms and has a protective effect on the brain edema caused by ischemic insult.
Methods: Brain edema was induced by the middle cerebral artery occlusion (MCAO); Natrii sulfas was administered once after the MCAO. At 3, 6, 15, 24, 48 hours after reperfusion, physiological indexes such as fecal weight, urine volume and water content in stool were assessed, and at 48 hours after reperfusion the edema index was measured.
Results:
1. Purgation therapy with Natrii sulfas significantly improved the reduction of fecal weight caused by ischemic insult (P<0.05).
2. Purgation therapy with Natrii sulfas significantly improved the reduction of urine volume caused by ischemic insult (P<0.05).
3. Purgation therapy with Natrii sulfas significantly improved the reduction of water content in stool caused by ischemic insult (P<0.05).
4. Purgation therapy with Natrii sulfas did not improve the neurological symptom caused by ischemic insult.
5. Purgation therapy with Natrii sulfas did not attenuate the total infarct volume caused by ischemic insult.
6. Purgation therapy with Natrii sulfas attenuated the brain edema caused by ischemic insult (P<0.05).
Conclusions: These results suggest that purgation therapy with Natrii sulfas improves some important symptoms and has a protective effect on the brain edema caused by ischemic insult.
목차
서론
재료 및 방법
결과
고찰
결론
참고문헌
참고문헌 (35)
참고문헌 신청
1. [단행본] - 전국한의과대학 본초학교수 / 1994 / 본초학 / 영림사 : 244 ~ 245
2. [학술지(정기간행물)] - Hwang CW / 1994 / A Literatual study on the Emergency care and Administration method of Medical emergency / Hye Hwa Medicine 1 (3) : 16 ~ 45
3. [단행본] - 김영석 / 1997 / 임상중풍학 / 서원당 : 303 ~ 348
4. [학술지(정기간행물)] - Koo BS / 2000 / Effects of Daeseungkitang on Constipated Stroke Patients / The Journal of Korean Oriental Medicine 21 (2) : 3 ~ 13
5. [학술지(정기간행물)] - 申錦林 / 1998 / 黃液直腸摘注治療急性腦出血的療效觀察 / 中醫藥 硏究 14 (1) : 27 ~ 28
2. [학술지(정기간행물)] - Hwang CW / 1994 / A Literatual study on the Emergency care and Administration method of Medical emergency / Hye Hwa Medicine 1 (3) : 16 ~ 45
3. [단행본] - 김영석 / 1997 / 임상중풍학 / 서원당 : 303 ~ 348
4. [학술지(정기간행물)] - Koo BS / 2000 / Effects of Daeseungkitang on Constipated Stroke Patients / The Journal of Korean Oriental Medicine 21 (2) : 3 ~ 13
5. [학술지(정기간행물)] - 申錦林 / 1998 / 黃液直腸摘注治療急性腦出血的療效觀察 / 中醫藥 硏究 14 (1) : 27 ~ 28
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UCI(KEPA) : I410-ECN-0101-2014-519-000261815