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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.9
- 수록면
- 501 - 510 (10page)
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This paper reviews a current view regarding the association between periodontitis and atherosclerotic cardiovascular diseases (ACVD). Many evidences have suggested that there exist biological mechanisms by which periodontitis can lead to ACVD. Periodontal infection can lead to direct bacterial invasion into endothelial tissues through the blood stream, then the bacteria can activate the host inflammatory response followed by atheroma formation, maturation and exacerbation. Also, chronic periodontal infections may indirectly induce endothelial activation or dysfunction through a state of systemic inflammation as evidenced by elevated plasma acute proteins, IL-6 and fibrinogen as well. There is moderate evidence that periodontal treatment can reduce systemic inflammation and improvement of both clinical surrogate markers. But there is no periodontal intervention study available on primary ACVD prevention. There is consistent and strong epidemiologic evidence, including in vitro, animal and clinical studies, that periodontitis imparts increased risk for future ACVD. However, evidences from intervention trials to date are not sufficient to confirm the multi directional causality of periodontitis in ACVD etiology. Well-designed intervention trials on the impact of periodontal treatment on the prevention of ACVD outcomes are needed.
목차
ABSTRACT
Ⅰ. 서론
Ⅱ. 연구방법
Ⅳ. 결론
참고문헌
참고문헌 (24)
참고문헌 신청
Lockhart P / 2012 / on behalf of the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, Council on Epidemiology and Prevention, Council on Peripheral Vascular Disease, and Council on Clinical Cardiology. Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association? A Scientific Statement From the American Heart Association / Circulation 125(20):2520~2544
Tonetti MS / 2013 / Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases / Journal of clinical periodontology 40(s14):S24~S29
Mattila KJ / 1989 / Association between dental health and acute myocardial infarction / BMJ: British Medical Journal 298(6676):779
Tonetti M / 2005 / Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research / Journal of clinical periodontology 32(s6):210~213
Eke P / 2012 / Prevalence of periodontitis in adults in the United States: 2009 and 2010 / Journal of dental research 91(10):914~920
Tonetti MS / 2013 / Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases / Journal of clinical periodontology 40(s14):S24~S29
Mattila KJ / 1989 / Association between dental health and acute myocardial infarction / BMJ: British Medical Journal 298(6676):779
Tonetti M / 2005 / Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research / Journal of clinical periodontology 32(s6):210~213
Eke P / 2012 / Prevalence of periodontitis in adults in the United States: 2009 and 2010 / Journal of dental research 91(10):914~920
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UCI(KEPA) : I410-ECN-0101-2014-510-002421216