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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.6
- 수록면
- 95 - 102 (8page)
- DOI
- 10.14815/kjdm.2013.06.40.2.95
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초록· 키워드
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This study was purposed to evaluate the cytotoxicity of commercially available 3 types of prefabricated gutta-percha points and 8 types of thermoplastic endodontic obturation materials using MTT tests and agar overlay test.
On MTT test, the Obtura<SUP>®</SUP> showed significantly lower cell viability (16.3±0.8% vs. Control; p＜0.05), which is over four times lower than those of other tested materials (p＜0.05). The Diadent point<SUP>®</SUP>, Sure-endo point<SUP>®</SUP>, and Diadent Medium<SUP>®</SUP> showed rather higher cell viability compared to that of Control (p＜0.05).
On agar overlay test, Sure-endo Soft<SUP>®</SUP> and Sure-endo Hard<SUP>®</SUP> showed a lower cytotoxicity (decolorization index = 2) compared to other tested materials (decolorization index = 3), while all the tested materials ranked as ‘moderate cytotoxic’ (response index = 2/2 or 3/2).
From this study it is demonstrated that the endodontic obturation materials have various degrees of cytotoxicity, and further in vivo biocompatibility evaluation is needed.
On MTT test, the Obtura<SUP>®</SUP> showed significantly lower cell viability (16.3±0.8% vs. Control; p＜0.05), which is over four times lower than those of other tested materials (p＜0.05). The Diadent point<SUP>®</SUP>, Sure-endo point<SUP>®</SUP>, and Diadent Medium<SUP>®</SUP> showed rather higher cell viability compared to that of Control (p＜0.05).
On agar overlay test, Sure-endo Soft<SUP>®</SUP> and Sure-endo Hard<SUP>®</SUP> showed a lower cytotoxicity (decolorization index = 2) compared to other tested materials (decolorization index = 3), while all the tested materials ranked as ‘moderate cytotoxic’ (response index = 2/2 or 3/2).
From this study it is demonstrated that the endodontic obturation materials have various degrees of cytotoxicity, and further in vivo biocompatibility evaluation is needed.
목차
ABSTRACT
서론
재료 및 방법
결과
고찰
결론
참고문헌
참고문헌 (35)
참고문헌 신청
1. [단행본] - 대한치과근관치료학회 / 2011 / 최신 근관치료학 / 덴탈위즈덤 : 259 ~ 310
2. [단행본] - Anusavice KJ / 2006 / Phillips' Science of Dental Materials / Elsevier : 188 ~ 190
3. [학술지(정기간행물)] - Bodrumlu E / 2008 / The response of subcutaneous connective tissue to a new endodontic filling material / J Biomed Mater Res B Appl Biomater 84 (2) : 463 ~ 467
4. [학술지(정기간행물)] - Brackett MG / 2008 / Cytotoxicity of endodontic materials over 6‐ weeks ex vivo / Int Endod J 41 (12) : 1072 ~ 1078
5. [학술지(정기간행물)] - Briseño BM / 1990 / Root canal sealer cytotoxicity on human gingival fibroblasts: I. Zinc oxide-eugenol-based sealers / J Endod 16 (8) : 383 ~ 386
2. [단행본] - Anusavice KJ / 2006 / Phillips' Science of Dental Materials / Elsevier : 188 ~ 190
3. [학술지(정기간행물)] - Bodrumlu E / 2008 / The response of subcutaneous connective tissue to a new endodontic filling material / J Biomed Mater Res B Appl Biomater 84 (2) : 463 ~ 467
4. [학술지(정기간행물)] - Brackett MG / 2008 / Cytotoxicity of endodontic materials over 6‐ weeks ex vivo / Int Endod J 41 (12) : 1072 ~ 1078
5. [학술지(정기간행물)] - Briseño BM / 1990 / Root canal sealer cytotoxicity on human gingival fibroblasts: I. Zinc oxide-eugenol-based sealers / J Endod 16 (8) : 383 ~ 386
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