지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 59 - 65 (7page)
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초록· 키워드
오류제보하기
Discriminating between two herbal medicines (Panax ginseng and Panax quinquefolius), with similar chemical and physical properties but different therapeutic effects, is a very serious and difficult problem. Differentiation between two processed ginseng genera is even more difficult because the characteristics of their appearance are very similar. An ultraperformance liquid chromatography-quadrupole time-offlight mass spectrometry (UPLC-QTOF MS)-based metabolomic technique was applied for the metabolite profiling of 40 processed P. ginseng and processed P. quinquefolius. Currently known biomarkers such as ginsenoside Rf and F11 have been used for the analysis using the UPLC-photodiode array detector. However, this method was not able to fully discriminate between the two processed ginseng genera. Thus, an optimized UPLC-QTOF-based metabolic profiling method was adapted for the analysis and evaluation of two processed ginseng genera. As a result, all known biomarkers were identified by the proposed metabolomics, and additional potential biomarkers were extracted from the huge amounts of global analysis data. Therefore, it is expected that such metabolomics techniques would be widely applied to the ginseng research field.
목차
ABSTRACT
1. Introduction
2. Materials and methods
3. Results and discussion
References
참고문헌 (28)
참고문헌 신청
1. [단행본] - Soldati F / 2000 / Biologically active natural products / CRC Press : 209 ~ 232
2. [학술지(정기간행물)] - 백인호 / 2013 / The world ginseng market and the ginseng (Korea) / Journal of Ginseng Research 37 (1) : 1 ~ 7
3. [학술지(정기간행물)] - Chan TWD / 2000 / Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS / Anal Chem 72 : 1281 ~ 1287
4. [학술지(정기간행물)] - Leung Kelvin SY / 2007 / Application of atmospheric pressure chemical ionization mass spectrometry in the identification and differentiation of Panax species / Phytochem Anal 18 : 146 ~ 150
5. [학술지(정기간행물)] - Li L / 2010 / Rapid qualitative and quantitative analyses of Asian ginseng in adulterated American ginseng preparations by UPLC/Q-TOF-MS / J Pharm Biomed Anal 52 : 66 ~ 72
2. [학술지(정기간행물)] - 백인호 / 2013 / The world ginseng market and the ginseng (Korea) / Journal of Ginseng Research 37 (1) : 1 ~ 7
3. [학술지(정기간행물)] - Chan TWD / 2000 / Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS / Anal Chem 72 : 1281 ~ 1287
4. [학술지(정기간행물)] - Leung Kelvin SY / 2007 / Application of atmospheric pressure chemical ionization mass spectrometry in the identification and differentiation of Panax species / Phytochem Anal 18 : 146 ~ 150
5. [학술지(정기간행물)] - Li L / 2010 / Rapid qualitative and quantitative analyses of Asian ginseng in adulterated American ginseng preparations by UPLC/Q-TOF-MS / J Pharm Biomed Anal 52 : 66 ~ 72
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UCI(KEPA) : I410-ECN-0101-2015-520-001297401