지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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The purpose of this study is to investigate effects of Red Ginseng-Ejung-tang (RE) on nitric oxide (NO) and hydrogen peroxide production in RAW 264.7 mouse macrophages induced by lipopolysaccharide (LPS). Cell viability was measured by modified MTT assay. NO production was measured by Griess reagent assay. Hydrogen peroxide production was measured by dihydrorhodamine 123 (DHR) assay. RE did not show cell toxicity against RAW 264.7 for 24 hr incubation at the concentrations of 10, 25, 50, 100, and 200 ㎍/mL in RAW 264.7. RE significantly inhibited NO production for 24 hr incubation at the concentrations of 10, 25, 50, and 100 ㎍/mL in RAW 264.7 (P < 0.05). RE significantly inhibited the LPS-induced production of NO for 24 hr incubation at the concentrations of 10, 25, 50, and 100 ㎍/mL in RAW 264.7 (P < 0.05). RE significantly inhibited the LPS-induced production of hydrogen peroxide for 16, 24, 40, 48, 64, and 72 hr incubation at the concentrations of 50, 100, and 200 ㎍/mL in RAW 264.7 (P < 0.05). These results suggest that RE has anti-inflammatory property related with its inhibition of NO and hydrogen peroxide production in LPS-induced macrophages.
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참고문헌
참고문헌 (18)
참고문헌 신청
1. [단행본] - 顧武軍 / 2000 / 현대상한론 / 한의문화사 : 647 ~ 649
2. [단행본] - 廣州中醫學院 / 1990 / 方劑學 / 영림사 : 144 ~ 146
3. [학술지(정기간행물)] - Jiang, J.P. / 2010 / Bovine adrenal medulla 22 attenuates hyperalgesia in the early phase of complete Freund's adjuvant-induced inflammation in rats / Sheng Li Xue Bao 63 (1) : 9 ~ 19
4. [학술지(정기간행물)] - Tufekci, K.U. / 2011 / The endotoxin-induced neuroinflammation model of Parkinson's disease / Parkinsons Dis 2011 : 487450 ~
5. [학술지(정기간행물)] - Gupta, Y.K. / 2011 / Potential of immunosuppressive agents in cerebral ischaemia / Indian J Med Res 133 (1) : 15 ~ 26
2. [단행본] - 廣州中醫學院 / 1990 / 方劑學 / 영림사 : 144 ~ 146
3. [학술지(정기간행물)] - Jiang, J.P. / 2010 / Bovine adrenal medulla 22 attenuates hyperalgesia in the early phase of complete Freund's adjuvant-induced inflammation in rats / Sheng Li Xue Bao 63 (1) : 9 ~ 19
4. [학술지(정기간행물)] - Tufekci, K.U. / 2011 / The endotoxin-induced neuroinflammation model of Parkinson's disease / Parkinsons Dis 2011 : 487450 ~
5. [학술지(정기간행물)] - Gupta, Y.K. / 2011 / Potential of immunosuppressive agents in cerebral ischaemia / Indian J Med Res 133 (1) : 15 ~ 26
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