지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.86 No.6
- 발행연도
- 2014.6
- 수록면
- 283 - 288 (6page)
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초록· 키워드
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Purpose: Early recurrence after hepatectomy is a well-known poor prognostic factor in patients with hepatocellular carcinoma. This study was undertaken to identify the risk factors of early recurrence in patients with hepatocellular carcinoma after hepatectomy.
Methods: One hundred and sixty-seven patients that underwent hepatectomy for hepatocellular carcinoma from January 2005 to December 2010 were enrolled. The numbers of patients with or without early recurrence group were 40 and 127, respectively. Clinico-pathologic factors were retrospectively analyzed.
Results: Potential risk factors were classified as host, tumor, or surgical factors. Of the host factors examined, lobular hepatitis activity was found to be a significant risk factor of early recurrence, and of the tumor factors, infiltrative type of gross appearance, level of preoperative AFP and worst Edmondson-Steiner grade were significant.
Conclusion: The present study shows that an infiltrative gross appearance, a high preoperative AFP level, high lobular hepatitis activity, and a poor Edmondson-Steiner grade are independent risk factors of early recurrence. Accordingly, patients with these risk factors should be followed closely after hepatectomy.
Methods: One hundred and sixty-seven patients that underwent hepatectomy for hepatocellular carcinoma from January 2005 to December 2010 were enrolled. The numbers of patients with or without early recurrence group were 40 and 127, respectively. Clinico-pathologic factors were retrospectively analyzed.
Results: Potential risk factors were classified as host, tumor, or surgical factors. Of the host factors examined, lobular hepatitis activity was found to be a significant risk factor of early recurrence, and of the tumor factors, infiltrative type of gross appearance, level of preoperative AFP and worst Edmondson-Steiner grade were significant.
Conclusion: The present study shows that an infiltrative gross appearance, a high preoperative AFP level, high lobular hepatitis activity, and a poor Edmondson-Steiner grade are independent risk factors of early recurrence. Accordingly, patients with these risk factors should be followed closely after hepatectomy.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (27)
참고문헌 신청
1. [학술지(정기간행물)] - Llovet JM. / 2003 / Hepatocellular carcinoma / Lancet 362 : 1907 ~ 1917
2. [학술지(정기간행물)] - Bruix J. / 2005 / Management of hepatocellular carcinoma / Hepatology 42 : 1208 ~ 1236
3. [학술지(정기간행물)] - Poon RT. / 1999 / Intrahepatic recurrence after curative resection of hepatocellular carcinoma : long-term results of treatment and prognostic factors / Ann Surg 229 : 216 ~ 222
4. [학술지(정기간행물)] - Imamura H. / 2003 / Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy / J Hepatol 38 : 200 ~ 207
5. [학술지(정기간행물)] - Poon RT. / 2000 / Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma / Cancer 89 : 500 ~ 507
2. [학술지(정기간행물)] - Bruix J. / 2005 / Management of hepatocellular carcinoma / Hepatology 42 : 1208 ~ 1236
3. [학술지(정기간행물)] - Poon RT. / 1999 / Intrahepatic recurrence after curative resection of hepatocellular carcinoma : long-term results of treatment and prognostic factors / Ann Surg 229 : 216 ~ 222
4. [학술지(정기간행물)] - Imamura H. / 2003 / Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy / J Hepatol 38 : 200 ~ 207
5. [학술지(정기간행물)] - Poon RT. / 2000 / Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma / Cancer 89 : 500 ~ 507
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