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논문 기본 정보

자료유형
학술저널
저자정보
허유섭 (경남대학교) 이몽우 (경남대학교) 심경미 (경북대학교) 김기훈 (경북대학교)
저널정보
한국체육과학회 한국체육과학회지 한국체육과학회지 제23권 제3호 (자연과학 편)
발행연도
2014.6
수록면
1,211 - 1,222 (12page)

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초록· 키워드

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The purpose of this study was to identify the effects of activity of glucose transporter(GLUT4), skeletal muscle AMPK activity and level of blood variables a for administration of propolis and exercise during six weeks in diabetic rats. Sparague Dawley rats were divided into 4 groups as follows: control group(CON, n=7), Diabetic with streptozotocin(STZ, n=7), propolis administration after diabetic(STZP, n=7), propolis administration and exercise after diabetic(STZPE, n=7). The results were as follows: There was significantly decreased in body weight in STZ, STZPE, STZP compared to CON(p<.05). The level of triglyceride, total, cholesterol, glucose was more significant increased at three groups(by induced diabetic) than control group(p<.05). The level of insulin was more significant decreased the three groups than control group(p<.05) Meanwhile there was significantly decreased in STZPE and STZP. On the other hand, the activity of GLUT4 in skeletal muscle was significantly decreased by diabetes(p<.05), and STZPE group was significantly increased compared to STP group(p<.05). However, activity of AMPK in skeletal muscle, there was no difference among the groups. In conclusion, in this study apply to animals by administration of STZ-induced diabetes, the blood lipid and blood glucose to get a significant increased, and 6 weeks of treatment with propolis to exercise confirmed that it was effective to improve. GLUT4 expression in skeletal muscle of propolis alone in the treatment was more effective than exercise when applicable. As a result, it may brings anti-diabetes by propolis intake and regular exercise. Applied in this study to verify the effectiveness of propolis alone for treatment duration and dose of intake later in more depth through a variety of applications that should be addressed is considered.

목차

Abstract
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 결과
Ⅳ. 논의
Ⅴ. 결론
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UCI(KEPA) : I410-ECN-0101-2015-690-001656909