Purpose: This study investigates the relationship among stress, Yangsaeng and subjective happiness in female undergraduate nursing students in the Republic of Korea. Method: The subjects of this study were 283 female undergraduate nursing students in Korea. Data were collected using a self-reporting questionnaire. Data analysis included descriptive statistics, Pearson"s correlation coefficients, independent t-tests, one-way ANOVA, Scheffe test, Stepwise multiple regression and Cronbach"s α. Results: Yangsaeng negatively correlated with stress (r=-.299, p<.001) but positively correlated with subjective happiness (r=.440, p<.001). Stress negatively correlated with subjective happiness (r=-.238, p<.001). Stepwise multiple regression revealed that Yangsaeng and satisfaction with the field of nursing explained 25.4% of subjective happiness. Conclusion: The Yangsaeng oriental health care regimen could lower stress and heighten subjective happiness. Therefore, Yangsaeng could be recommended as a feasible means of promoting health and subjective happiness.