지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.12
- 수록면
- 759 - 767 (9page)
- DOI
- 10.17495/easdl.2014.12.24.6.759
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This study examined the effect of Momordica charantia L. (bitter melon: BM) on lipid and hepatic antioxidative enzyme levels in diabetic rats. Diabetes mellitus was induced in male Sprague-Dawley rats by injection of streptozotocin (STZ), and rats were fed for 4 weeks with experimental groups divided into four groups: a normal control group, STZ-control and STZBM 5% & STZ-BM 10% treated groups. Levels of free fatty acids (FFA), high-density lipoprotein cholesterol (HDL-chol), triglycerides (TG) in plasma and malondialdehyde (MDA) & protein in liver, catalase (CAT), superoxide dismutase (SOD), glutathione-S-transferase (GST), and xanthine oxidase (XOD) were measured in liver cytosol. Level of HDL-chol significantly increased in the STZ-BM 5% diabetic group. TG & FFA levels were significantly higher in all diabetic groups compared to the control group. MDA and protein levels were significantly higher in the STZ-BM 5% group compared to all other experimental group. CAT level was higher in the supplementary group with BM compared to the STZ-control group, although the difference was not significantly different. SOD level was not significant in any experimental groups. GST level was significantly higher in the BM-treated groups compared to the STZ-control group. XOD level was significantly lower in the BM 5% group and significantly decreased in all experimental groups. These results show that supplementation of BM fruit powder may have beneficial effects on diabetic complications and damage caused by oxidative stress.
목차
ABSTRACT
서론
재료 및 방법
결과 및 고찰
요약
REFERENCES
참고문헌 (56)
참고문헌 신청
1. [학술지(정기간행물)] - Aebi H / 1984 / Catalase in vitro / Methods Enzymol 105 : 121 ~ 126
2. [단행본] - Bergmeyer HU / 1974 / In the Methods of Enzymatic Analysis, Vol. 1 / Academic Press Inc. : 521 ~ 522
3. [학술지(정기간행물)] - Betteridge J / 2001 / Dyslipidaemia and diabetes / Prac Diabetes Intern 18 : 201 ~ 207
4. [학술지(정기간행물)] - Bowler C / 1992 / Superoxide dismutase and stress tolerance / Annual Review of Plant Physiology and Plant Molecular Biology 43 : 83 ~ 116
5. [학술지(정기간행물)] - Cefalu WT / 2008 / Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans / Endocr Metab Immune Disord Drug Targets 8 : 78 ~ 81
2. [단행본] - Bergmeyer HU / 1974 / In the Methods of Enzymatic Analysis, Vol. 1 / Academic Press Inc. : 521 ~ 522
3. [학술지(정기간행물)] - Betteridge J / 2001 / Dyslipidaemia and diabetes / Prac Diabetes Intern 18 : 201 ~ 207
4. [학술지(정기간행물)] - Bowler C / 1992 / Superoxide dismutase and stress tolerance / Annual Review of Plant Physiology and Plant Molecular Biology 43 : 83 ~ 116
5. [학술지(정기간행물)] - Cefalu WT / 2008 / Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans / Endocr Metab Immune Disord Drug Targets 8 : 78 ~ 81
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