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한국사회체육학회 한국사회체육학회지 한국사회체육학회지 제40권 제2호
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    초록·키워드

    Interleukin-8 (IL-8) is an inflammatory cytokine that acts as a chemokine on neutrophils. Increase of neutrophils and IL-8 induced by exercise. This study was designed to investigate the expression of interleukin-8 (IL-8) in plasma at resting and after acute intensive exercise in trained tennis players (Trained G) and untrained normal controls (Control G). All subjects underwent treadmill running for 30 min at 80% intensity of VO2max. Blood was drawn from peripheral vein for analyses. We analyzed the expression of mRNA and protein of IL-8 and evaluated the correlation between the number of neutrophils and plasma IL-8 level. Expressions of mRNA and protein of IL-8 were markedly higher in the Trained G as compared with the Control G at immediately after exercise, but not at before exercise, 30min and 120min after exercise). Except immediately after exercise, there was no correlation between the number of neutrophils and the plasma IL-8 concentration in both groups. Higher induced IL-8 after exercise in athletes may be caused by the adaptation to exercise training.

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