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(Korea University) (Korea University) (Korea University) (Korea University)
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한국생물공학회 한국생물공학회 학술대회 2015 한국생물공학회춘계학술발표대회 및 국제심포지엄
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    초록·키워드

    Cells influenced by extremely low-frequency electromagnetic fields (ELF-EMF) get lots of differences with normal cells in gene expression, cell fate determination, and even cell differentiation. The influence of ELF-EMF on bone marrow derived mesenchymal stem cells (BM-MSCs) has been investigated to understand the correlation with the enhancement of astrocytic differentiation. We also used BM-MSCs exposed to 50 Hz EMF to study the effect of ELF-EMF by different analytical methods. We focused on the expression levels of SIRT1 and its downstream molecules such as TLE1, HES1 and MASH1. ELF-EMF exposure significantly reduced the rate of proliferation and lifted that of differentiation. We found that GFAP as an astrocytic diff ... 전체 초록 보기

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      UCI(KEPA) : I410-ECN-0101-2016-470-001522502