지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.3
- 수록면
- 67 - 74 (8page)
이용수
초록· 키워드
오류제보하기
One hundred ninety-five rabies cases in cattle were identified in South Korea since 1993. As most of rabies cases have a relation to rabid Korean raccoon dogs (Nyctereutes procyonoides koreensis), vaccination to animals including cattle is mandatory in rabies risk region. In order to minimize fatal rabies in animals, eradication policy of the disease has been achieved by controlling reservoirs and by mass vaccination. In this study, we compared the antibody response in cattle and guinea pigs inoculated with rabies vaccines commercially available in Korea. Each group of cattle in Gangwon-do was vaccinated intramuscularly with either one of five commercial inactivated vaccines or a live attenuated rabies vaccine (designated as A to F). Serum samples at the time of vaccination and four weeks post vaccination were obtained from the cattle and guinea pigs and were analyzed with virus neutralizing assay (VNA). Each group of cattle inoculating rabies vaccines showed significant virus neutralizing antibody titers (p < 0.05) ranging from 1.55 to 17.8 mean IU/ml compared with the non-vaccinated cattle and guinea pigs inoculated with 1/20 dose of vaccine showed relatively low VN antibody titers ranging from 0.23 to 6.1 mean IU/ml. All cattle immunized with A, C and F showed high VN antibody titers over 0.5 IU/ml and 62.5% and 37.5% of cattle inoculated with D and E showed protective antibody titer, respectively. This finding suggests that the inactivated or live attenuated rabies vaccination commercially available in Korea could induce protective antibody response in Korean cattle, but sero-conversion rate and sero-positive rate showing VN antibody titer over 0.5 IU/ml depend on vaccines.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSIONS
REFERENCES
참고문헌 (26)
참고문헌 신청
1. [학술지(정기간행물)] - World Health Organization(WHO). / 1992 / WHO expert committee on rabies / World Health Organ Tech Rep Ser 824 : 1 ~ 84
2. [학술지(정기간행물)] - Johnson N. / 2003 / Rabies emergence among foxes in Turkey / J Wildl Dis 39 : 262 ~ 270
3. [학술지(정기간행물)] - Smith JS. / 1992 / Epidemiologic and historical relationships among 87 rabies virus isolates as determined by limited sequence analysis / J Infect Dis 166 : 296 ~ 307
4. [학술지(정기간행물)] - Sterner RT. / 2009 / Tactics and economics of wildlife oral rabies vaccination, Canada and the United States / Emerg Infect Dis 15 : 1176 ~ 1184
5. [학술지(정기간행물)] - Streicker DG. / 2012 / Variable evolutionary routes to host establishment across repeated rabies virus host shifts among bats / Proc Natl Acad Sci U S A 109 : 19715 ~ 19720
2. [학술지(정기간행물)] - Johnson N. / 2003 / Rabies emergence among foxes in Turkey / J Wildl Dis 39 : 262 ~ 270
3. [학술지(정기간행물)] - Smith JS. / 1992 / Epidemiologic and historical relationships among 87 rabies virus isolates as determined by limited sequence analysis / J Infect Dis 166 : 296 ~ 307
4. [학술지(정기간행물)] - Sterner RT. / 2009 / Tactics and economics of wildlife oral rabies vaccination, Canada and the United States / Emerg Infect Dis 15 : 1176 ~ 1184
5. [학술지(정기간행물)] - Streicker DG. / 2012 / Variable evolutionary routes to host establishment across repeated rabies virus host shifts among bats / Proc Natl Acad Sci U S A 109 : 19715 ~ 19720
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