지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.6
- 수록면
- 95 - 100 (6page)
이용수
초록· 키워드
오류제보하기
A red seaweed, Callophyllis japonica has been traditionally eaten in the oriental area. In a recent study, it has been demonstrated that the ethanol extract of C. japonica have antioxidant activity. However, there are few studies about the effects of C. japonica on the function of immune cells. We investigated the immunomodulatory effects of C. japonica on the function of dendritic cells, the potent antigen-presenting cells. Methods: Bone marrow-derived dendritic cells (DCs) were used and the viability was measured by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide assay and trypan blue exclusion test. Cytokine and nitric oxide (NO) levels were determined by using ELISA and Griess reagent, respectively. The expression levels of DC surface markers were measured by flow cytometric analysis. Results: C. japonica ethanol extract did not significantly affect the DCs viability and the IL-12 production from DCs, irrespective of the presence of lipopolysaccharide (LPS). In addition, it did not significantly change the expression of DC surface markers. However, C. japonica ethanol extract significantly inhibited the LPS-induced NO production and also increased the proliferation of allogeneic lymphocytes activated by DCs. Conclusion: Our data suggests that C. japonica ethanol extract enhances the proliferation of allogeneic lymphocytes activated by DCs which is associated with inhibition of NO production from DCs induced by LPS.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Ethanol extract of Callophyllis japonica enhances nitric oxide and tumor necrosis factor-alpha production in mouse macrophage cell line, RAW 264.7 cells
Oriental pharmacy and experimental medicine
2007 .01
-
볏붉은잎 추출물의 돼지 세균에 대한 항균효과
한국가축위생학회지
2009 .01
-
Torilin from Torilis japonica (Houtt.) DC. Blocks hKv1.5 Channel Current
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
-
마우스 동종 줄기세포 유래 수지상 세포를 이용한 백신의 흑색종 폐암 전이 모델에서의 항암 효과 및 기전 연구
Immune Network
2006 .09
-
Effects of Callophyllis japonica powder on carbon tetrachloride-induced liver injury in rats
Oriental pharmacy and experimental medicine
2005 .01
-
금은화 추출액이 RAW 264.7 Macrophage에서의 NO와 $PGE_2$ 생성에 미치는 영향
대한침구의학회지
2012 .01
-
Anti-inflammatory Effects of Extracts of Duchesnea chrysantha in Human Monocytic THP-1 Cells and Human Eosinophilic EoL-1 Cells
대한의생명과학회지
2013 .03
-
Inflammatory Mediators Modulate NK Cell-stimulating Activity of Dendritic Cells by Inducing Development of Polarized Effector Function
Immune Network
2007 .09
-
창출 추출물의 BV2 cell 소염작용에 관한 실험적 연구
한방안이비인후피부과학회지
2007 .01
-
Induction of CD4⁺ Regulatory and Polarized Effector/helper T Cells by Dendritic Cells
Immune Network
2016 .02
-
Alpha-Type 1 Polarized Dendritic Cells Loaded with Apoptotic Allogeneic Breast Cancer Cells Can Induce Potent Cytotoxic T Lymphocytes against Breast Cancer
Cancer Research and Treatment
2011 .01
-
Dendritic Cell as an effective cancer immuno-cell therapy module II. : Anti-tumor effect of cultured DCs in murine melanoma metastasis model
대한약학회 학술대회
2003 .01
-
Ginsenoside fractions regulate the action of monocytes and their differentiation into dendritic cells
Journal of Ginseng Research
2015 .07
-
Ginsenoside fractions regulate the action of monocytes and their differentiation into dendritic cells
Journal of Ginseng Research
2015 .01
-
Antitumor Activity of Lentivirus-mediated Interleukin -12 Gene Modified Dendritic Cells in Human Lung Cancer in Vitro
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
선학초(仙鶴草)추출물의 대식세포에서의 LPS-유도 염증반응에 대한 효능 연구
대한본초학회지(본초분과학회지)
2016 .01
-
비파엽 추출물의 항산화 효능과 성분분석
대한화장품학회지
2012 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0