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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.8
- 수록면
- 177 - 185 (9page)
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초록· 키워드
오류제보하기
Although rheumatoid arthritis (RA) is the most common chronic inflammatory autoimmune disease, diagnosis of RA is currently based on clinical manifestations, and there is no simple, practical assessment tool in the clinical field to assess disease activity and severity. Recently, there has been increasing interest in the discovery of new diagnostic RA biomarkers that can assist in evaluating disease activity, severity, and treatment response. Proteomics, the largescale study of the proteome, has emerged as a powerful technique for protein identification and characterization. For the past 10 years, proteomic techniques have been applied to different biological samples (synovial tissue/fluid, blood, and urine) from RA patients and experimental animal models. In this review, we summarize the current state of the application of proteomics in RA and its importance in identifying biomarkers and treatment targets.
목차
INTRODUCTION
PROTEOMICS
EXPLORATION OF NOVEL BIOMARKERS USING A PROTEOMIC APPROACH
CONCLUSION
REFERENCES
참고문헌 (60)
참고문헌 신청
[학술지(정기간행물)] - Smolen, J. S. / 2004 / Patients with rheumatoid arthritis in clinical care / Ann. Rheum. Dis 63 : 221 ~ 225
[학술지(정기간행물)] - Wolfe, F. / 2003 / Predicting mortality in patients with rheumatoid arthritis / Arthritis Rheum 48 : 1530 ~ 1542
[학술지(정기간행물)] - Pincus, T. / 1984 / Severe functional declines, work disability, increased mortality in seventy-five rheumatoid arthritis patients studied over nine years / Arthritis Rheum 27 : 864 ~ 872
[학술지(정기간행물)] - Sokka, T. / 2000 / Healing of erosions in rheumatoid arthritis / Ann. Rheum. Dis 59 : 647 ~ 649
[학술지(정기간행물)] - Rau, R. / 2001 / Identification of radiologic healing phenomena in patients with rheumatoid arthritis / J. Rheumatol 28 : 2608 ~ 2615
[학술지(정기간행물)] - Wolfe, F. / 2003 / Predicting mortality in patients with rheumatoid arthritis / Arthritis Rheum 48 : 1530 ~ 1542
[학술지(정기간행물)] - Pincus, T. / 1984 / Severe functional declines, work disability, increased mortality in seventy-five rheumatoid arthritis patients studied over nine years / Arthritis Rheum 27 : 864 ~ 872
[학술지(정기간행물)] - Sokka, T. / 2000 / Healing of erosions in rheumatoid arthritis / Ann. Rheum. Dis 59 : 647 ~ 649
[학술지(정기간행물)] - Rau, R. / 2001 / Identification of radiologic healing phenomena in patients with rheumatoid arthritis / J. Rheumatol 28 : 2608 ~ 2615
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UCI(KEPA) : I410-ECN-0101-2016-511-001834838