지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.10
- 수록면
- 26 - 30 (5page)
이용수
초록· 키워드
오류제보하기
Background: Primary tracheal tumors occur infrequently, accounting for less than 0.1% of all tumors. Adenoid cystic carcinoma (ACC) is the second most common type of malignancy of the trachea after squamous cell carcinoma (SCC). Little has been reported on the risk factors for tracheal ACC. The purpose of this study is to describe a case of tracheal ACC in a patient who had been exposed to rubber fumes, and to review the relationship between tracheal ACC and rubber fumes.
Case report: A 48-year-old man who had been experiencing aggravation of dyspnea for several months was diagnosed as having ACC of the trachea on the basis of a pathologic examination of a biopsy specimen obtained via laser microscopy-guided resection. The patient had been exposed to rubber fumes for 10 years at a tire manufacturing factory where he worked until ACC was diagnosed. His job involved preheating and changing rubber molds during the curing process.
Conclusion: ACC of both the trachea and the salivary glands show very similar patterns with regard to histopathology and epidemiology and are therefore assumed to have a common etiology. Rubber manufacturing is an occupational risk factor for the development of salivary gland tumors. Further, rubber fumes have been reported to be mutagenic. The exposure level to rubber fumes during the curing process at the patient’s workplace was estimated to be close to or higher than British Occupational Exposure Limits. Therefore, tracheal ACC in this case might have been influenced by occupational exposure to rubber fumes.
Case report: A 48-year-old man who had been experiencing aggravation of dyspnea for several months was diagnosed as having ACC of the trachea on the basis of a pathologic examination of a biopsy specimen obtained via laser microscopy-guided resection. The patient had been exposed to rubber fumes for 10 years at a tire manufacturing factory where he worked until ACC was diagnosed. His job involved preheating and changing rubber molds during the curing process.
Conclusion: ACC of both the trachea and the salivary glands show very similar patterns with regard to histopathology and epidemiology and are therefore assumed to have a common etiology. Rubber manufacturing is an occupational risk factor for the development of salivary gland tumors. Further, rubber fumes have been reported to be mutagenic. The exposure level to rubber fumes during the curing process at the patient’s workplace was estimated to be close to or higher than British Occupational Exposure Limits. Therefore, tracheal ACC in this case might have been influenced by occupational exposure to rubber fumes.
목차
Abstract
Background
Case presentation
Conclusion
References
참고문헌 (24)
참고문헌 신청
1. [학술지(정기간행물)] - Urdaneta AI / 2011 / Population based cancer registry analysis of primary tracheal carcinoma / Am J Clin Oncol 34 (1) : 32 ~ 37
2. [학술지(정기간행물)] - Honings J / 2007 / Incidence and treatment of tracheal cancer: a nationwide study in the Netherlands / Ann Surg Oncol 14 (2) : 968 ~ 976
3. [학술지(정기간행물)] - Manninen MP / 1991 / Occurrence of tracheal carcinoma in Finland / Acta Otolaryngol 111 (6) : 1162 ~ 1169
4. [학술지(정기간행물)] - Licht PB / 2001 / Tracheal cancer in Denmark: a nationwide study / Eur J Cardio-Thorac Surg 19 (3) : 339 ~ 345
5. [학술지(정기간행물)] - Webb BD / 2006 / Primary tracheal malignant neoplasms: the university of Texas MD Anderson cancer center experience / J Am Coll Surg 202 (2) : 237 ~ 246
2. [학술지(정기간행물)] - Honings J / 2007 / Incidence and treatment of tracheal cancer: a nationwide study in the Netherlands / Ann Surg Oncol 14 (2) : 968 ~ 976
3. [학술지(정기간행물)] - Manninen MP / 1991 / Occurrence of tracheal carcinoma in Finland / Acta Otolaryngol 111 (6) : 1162 ~ 1169
4. [학술지(정기간행물)] - Licht PB / 2001 / Tracheal cancer in Denmark: a nationwide study / Eur J Cardio-Thorac Surg 19 (3) : 339 ~ 345
5. [학술지(정기간행물)] - Webb BD / 2006 / Primary tracheal malignant neoplasms: the university of Texas MD Anderson cancer center experience / J Am Coll Surg 202 (2) : 237 ~ 246
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UCI(KEPA) : I410-ECN-0101-2016-517-001952899