지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.12
- 수록면
- 165 - 171 (7page)
이용수
초록· 키워드
오류제보하기
Microbial pathogens are responsible for most of the rapidly-spreading deadly infectious diseases against humans. Thus, there is an urgent need for efficient and rapid detection methods for infectious microorganisms. The detection methods should not only be targeted and specific, but they have to be encompassing of potential changes of the pathogen as it evolves and mutates quickly during an epidemic or pandemic. The existing diagnostics such as the antibody-based ELISA immunoassay and PCR methods are too selective and narrowly focused; they are insufficient to capture newly evolved mutant strains of the pathogen. Here, we introduce a fresh perspective on some new technologies, including aptamers and next generation sequencing for pathogen detection. These technologies are not in their infancy; they are reasonably mature and ready, and they hold great promise for unparalleled applications in pathogen detection.
목차
INTRODUCTION
Can aptamers provide more superior pathogen diagnostics than antibodies?
Next Generation Sequencing, a robust tool in pathogen gene detection/identification
CONCLUSION
REFERENCES
참고문헌 (36)
참고문헌 신청
[학술지(정기간행물)] - Abbaspour A / 2015 / Aptamerconjugated silver nanoparticles for electrochemical dualaptamer-based sandwich detection of Staphylococcus aureus / Biosens Bioelectron 68 : 149 ~ 155
[학술지(정기간행물)] - Acquah C / 2015 / A review on immobilised aptamers for high throughput biomolecular detection and screening / Anal Chim Acta 888 : 10 ~ 18
[학술지(정기간행물)] - Akira S / 2001 / Toll-like receptors: critical proteins linking innate and acquired immunity / Nat Immunol 2 : 675 ~ 680
[학술지(정기간행물)] - Bruno JG / 2015 / Predicting the uncertain future of aptamer-based diagnostics and therapeutics / Molecules 20 : 6866 ~ 6887
[학술지(정기간행물)] - Cho S / 2005 / Bis-aptazyme sensors for hepatitis C virus replicase and helicase without blank signal / Nucleic Acids Res 33 : e177 ~
[학술지(정기간행물)] - Acquah C / 2015 / A review on immobilised aptamers for high throughput biomolecular detection and screening / Anal Chim Acta 888 : 10 ~ 18
[학술지(정기간행물)] - Akira S / 2001 / Toll-like receptors: critical proteins linking innate and acquired immunity / Nat Immunol 2 : 675 ~ 680
[학술지(정기간행물)] - Bruno JG / 2015 / Predicting the uncertain future of aptamer-based diagnostics and therapeutics / Molecules 20 : 6866 ~ 6887
[학술지(정기간행물)] - Cho S / 2005 / Bis-aptazyme sensors for hepatitis C virus replicase and helicase without blank signal / Nucleic Acids Res 33 : e177 ~
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UCI(KEPA) : I410-ECN-0101-2016-510-002321953