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학술저널
저자정보
Juha Song (Seoul National University) C-Yoon Kim (Seoul National University) Seo-Na Chang (Seoul National University) Tamer Said Abdelkader (Seoul National University) Juhee Han (Seoul National University) Tae-Hyun Kim (Seoul National University) Hanseul Oh (Seoul National University) Ji Min Lee (Seoul National University) Dong-Su Kim (Shinpoong Pharmaceutical Co. Ltd.) Jong-Taek Kim (Kangwon National University) Hong-Shik Oh (Jeju National University) Moonsuk Hur (National Institute of Environmental Research) Jae-Hwa Suh (National Institute of Environmental Research) Jae-Hak Park (Seoul National University)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.53 No.6
발행연도
2015.12
수록면
737 - 743 (7page)

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In order to examine the prevalence of Cryptosporidium infection in wild rodents and insectivores of South Korea and to assess their potential role as a source of human cryptosporidiosis, a total of 199 wild rodents and insectivore specimens were collected from 10 regions of South Korea and screened for Cryptosporidium infection over a period of 2 years (2012-2013). A nested-PCR amplification of Cryptosporidium oocyst wall protein (COWP) gene fragment revealed an overall prevalence of 34.2% (68/199). The sequence analysis of 18S rRNA gene locus of Cryptosporidium was performed from the fecal and cecum samples that tested positive by COWP amplification PCR. As a result, we identified 4 species/genotypes; chipmunk genotype I, cervine genotype I, C. muris, and a new genotype which is closely related to the bear genotype. The new genotype isolated from 12 Apodemus agrarius and 2 Apodemus chejuensis was not previously identified as known species or genotype, and therefore, it is supposed to be a novel genotype. In addition, the host spectrum of Cryptosporidium was extended to A. agrarius and Crosidura lasiura, which had not been reported before. In this study, we found that the Korean wild rodents and insectivores were infected with various Cryptosporidium spp. with large intra-genotypic variationa, indicating that they may function as potential reservoirs transmitting zoonotic Cryptosporidium to livestock and humans.

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