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(양산병원) (양산병원) (부산대학교병원) (부산대학교병원) (부산대학교병원) (부산대학교병원) (부산대학교병원) (부산대학교병원) (부산대학교병원) (양산병원)
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대한생물치료정신의학회 생물치료정신의학 생물치료정신의학 제22권 제1호
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    초록·키워드

    Objectives:There are some evidences that patients with bipolar depression experience more stressful life events than patients with unipolar depression do. However, there is lack of evidence that bipolarity in depressive patients is associated with more frequent and severe stressful life events. The current study is aimed to compare life events and perceived stress according to the Bipolar Spectrum Diagnostic Scale(BSDS) results in depressive patients.
    Methods:A total of 102 patients who have experienced major depressive episodes were recruited. Two groups with or without positive screening of Bipolar Spectrum Diagnostic Scale(BSDS) were divided. Stress-related factors were measured by the Life Experiences Survey(LES) and Perceived Stress Scale(PSS).
    Results:Patients with depressive disorders who screened positive on the BSDS showed more life events(p=.006) and higher impact of life events(p=.005) checked on the LES, and higher score on the PSS negative perception subscale(p=.010) than those who screened negative on the BSDS did. After the adjustment of Beck Depression Inventory(BDI), depressive patients with BSDS(+) experienced more life events(p=.019) and higher impact of life events(p=.029) than those with BSDS(-). However, the difference of PSS negative perception subscale between two groups disappeared after adjusting the effects of depressive symptoms.
    Conclusion:These results suggest that depressive patients with positive screening of BSDS may response to life events in negative ways and feel more stressful. The positive screening of BSDS in depressive patients can affect their trajectories of depression. Further, large scale and prospective studies are needed to clarify these relationships between bipolar spectrum disorder and stress.

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      UCI(KEPA) : I410-ECN-0101-2016-513-002672654