지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.90 No.5
- 발행연도
- 2016.5
- 수록면
- 279 - 286 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: Intraoperative assessment of tissue perfusion is important to predict wound healing or improvement of symptoms in patients with peripheral arterial disease (PAD) or vascular trauma. There is no widely accepted standard for intraoperative measurement of tissue perfusion. Here, we report the use of indocyanine green (ICG)-based angiography to determine the blood flow in patients with PAD and vascular trauma.
Methods: The SPY fluorescent imaging system was utilized. A dose of 3–5 mL of ICG (2.5 mg/mL) was injected intravenously followed by a 10-mL normal saline flush. The SPY imaging system was used to quantitatively assess perfusion. During the study period, the SPY imaging system was applied in 4 patients with PAD and one patient with vascular trauma.
Results: In 3 patients with PAD associated with an ischemic wound, complete wound healing was achieved with the indication of viable tissue by the SPY system. In one patient with severe claudication in both lower extremities, the ICG angiography was used to determine the increased blood flow after revascularization. In the case of vascular trauma, this imaging system enabled the delineation of viability of the injured tissue.
Conclusion: ICG angiography can determine the surface tissue viability in PAD patients. In cases of severe vascular trauma, the SPY system can be used to determine tissue perfusion. Further study is warranted to define the definite utility of this technology to assess perfusion, response to revascularization, and potentially, to predict the likelihood of wound healing.
Methods: The SPY fluorescent imaging system was utilized. A dose of 3–5 mL of ICG (2.5 mg/mL) was injected intravenously followed by a 10-mL normal saline flush. The SPY imaging system was used to quantitatively assess perfusion. During the study period, the SPY imaging system was applied in 4 patients with PAD and one patient with vascular trauma.
Results: In 3 patients with PAD associated with an ischemic wound, complete wound healing was achieved with the indication of viable tissue by the SPY system. In one patient with severe claudication in both lower extremities, the ICG angiography was used to determine the increased blood flow after revascularization. In the case of vascular trauma, this imaging system enabled the delineation of viability of the injured tissue.
Conclusion: ICG angiography can determine the surface tissue viability in PAD patients. In cases of severe vascular trauma, the SPY system can be used to determine tissue perfusion. Further study is warranted to define the definite utility of this technology to assess perfusion, response to revascularization, and potentially, to predict the likelihood of wound healing.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (20)
참고문헌 신청
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Mothes H, Dönicke T, Friedel R, Simon M,
Markgraf E, Bach O. Indocyanine-green
fluorescence video angiography used
clinically to evaluate tissue perfusion in
microsurgery. J Trauma 2004;57:1018-24.
Lee JY, Lee SW, Lee WS, Han S, Park YK,
Kwon CH, et al. Prevalence and clinical
implications of newly revealed, asymptomatic
abnormal ankle-brachial index in
patients with significant coronary artery
disease. JACC Cardiovasc Interv 2013;6:
1303-13.
Park IH, Lee SC, Park IS, Nam CH, Ahn HS,
Park HY, et al. Asymptomatic peripheral
vascular disease in total knee arthroplasty:
preoperative prevalence and risk
factors. J Orthop Traumatol 2015;16:23-6.
Jallali N, Ridha H, Butler PE. Postoperative
monitoring of free flaps in UK plastic
surgery units. Microsurgery 2005;25:469-
72.
Mothes H, Dönicke T, Friedel R, Simon M,
Markgraf E, Bach O. Indocyanine-green
fluorescence video angiography used
clinically to evaluate tissue perfusion in
microsurgery. J Trauma 2004;57:1018-24.
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UCI(KEPA) : I410-ECN-0101-2016-514-002860706