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논문 기본 정보

자료유형
학술저널
저자정보
Youn Ju Lee (Catholic University of Daegu) Jae-Seok Jang (Catholic University of Daegu) Jae-Ho Yang (Catholic University of Daegu)
저널정보
한국해양바이오학회 한국해양바이오학회지 한국해양바이오학회지 제8권 제1호
발행연도
2016.6
수록면
10 - 17 (8page)

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초록· 키워드

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A wide-spread contamination of persistent organic pollutants (POPs) such as dioxins, PCBs, PBDEs in the aquatic ecosystem has generated a great concern over the potential risk for these substances to impact marine biotas and food web. Since a major exposure route of these substances to the humans is through the consumption of food including fish and marine byproducts, the consumption of contaminated products has been a great public health concern. Exposure to POPs has been associated with a wide spectrum of adverse effects including reproductive, developmental, immunologic, carcinogenic, and neurotoxic effects. This review covers the background information of key POPs substances and the recent development of toxicity studies including the mode of action. Because neurotoxic effects of some POPs have been observed in humans at low concentrations, polychlorinated biphenyl (PCB), a representative chemical of POPs, is focused to discuss the possible mode(s) of action for the neurotoxic effects. This review provides the updates of toxicity studies on POPs and paves ways to discuss a possible implication of contaminated marine biota over the human health among the marine biotechnology researchers.

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Abstract
Introduction
Sources of Persistent Organic Pollutants (POPs)
Toxic equivalency factors (TEFs)
Common mechanism of action for Dioxin-like compounds
Evidence of neurotoxicity following exposure to PCBs
Neurochemical effects
Discussion
Conclusion
References

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UCI(KEPA) : I410-ECN-0101-2017-472-000873939