지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.6
- 수록면
- 126 - 134 (9page)
이용수
초록· 키워드
오류제보하기
To examine the possibility of using Musa sapientum L. (Banana) leaf extract as a cosmetic raw material, banana leaves grown in Jeju Island were extracted with 70% ethanol. Polysaccharides present in banana leaf extract were discarded by precipitation with cold ethanol. Polysaccharidediscarded banana leaf extract promoted procollagen and COL1A1 gene expression, but inhibited matrix metalloproteinase (MMP)-1 and MMP-2 gene expression in human skin fibroblasts when examined by real-time reverse-transcription polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). The active compound in banana leaves was identified by fractionation with various solvents. The chloroform fraction showed the highest anti-wrinkle efficacy and the active compound of chloroform fraction was identified as corosolic acid by NMR, FT-IR, EA, and HPLCMS. In addition, banana leaf extract showed anti-oxidative efficacy with an IC50 value of 67.91 ppm, as determined by DPPH free radical scavenging assay. Finally, the anti-wrinkle efficacy of banana leaf extract-containing cream was confirmed by clinical tests. Based on these results, banana leaves could have an application as a cosmetic raw material with anti-wrinkle efficacy.
목차
Abstract
1. INTRODUCTION
2. MATERIALS AND METHODS
3. RESULTS AND DISCUSSIONS
4. CONCLUSION
REFERENCES
참고문헌 (25)
참고문헌 신청
[학술지(정기간행물)] - Seo, J. Y. / 2003 / Enhanced expression of cylooxygenase-2by UV in aged human skin in vivo / Mech Ageing Dev 124 : 903 ~
[학술지(정기간행물)] - Nichols, J. A. / 2009 / Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms / Arch. Dermatol. Res 302 : 71 ~
[학술지(정기간행물)] - Md. Abul Hashem / 2008 / A Rapid and Sensitive Screening System for Human Type I Collagen with the Aim of Discovering Potent Anti-Aging or Anti-Fibrotic Compounds / Molecules and Cells 26 (6) : 625 ~ 630
[학술지(정기간행물)] - GA. Lullo. D. / 2002 / Mapping the ligand-binding sites and disease associated mutations on the most abundant protein in the human, type I collagen / J. Biol. Chem 277 : 4223 ~ 4231
[학술지(정기간행물)] - Jurkiewicz, B. A. / 1995 / Effect of topically applied tocopherol on ultraviolet radiation-mediated free radical damage in skin / J. Invest. Dermatol 104 : 484 ~ 488
[학술지(정기간행물)] - Nichols, J. A. / 2009 / Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms / Arch. Dermatol. Res 302 : 71 ~
[학술지(정기간행물)] - Md. Abul Hashem / 2008 / A Rapid and Sensitive Screening System for Human Type I Collagen with the Aim of Discovering Potent Anti-Aging or Anti-Fibrotic Compounds / Molecules and Cells 26 (6) : 625 ~ 630
[학술지(정기간행물)] - GA. Lullo. D. / 2002 / Mapping the ligand-binding sites and disease associated mutations on the most abundant protein in the human, type I collagen / J. Biol. Chem 277 : 4223 ~ 4231
[학술지(정기간행물)] - Jurkiewicz, B. A. / 1995 / Effect of topically applied tocopherol on ultraviolet radiation-mediated free radical damage in skin / J. Invest. Dermatol 104 : 484 ~ 488
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UCI(KEPA) : I410-ECN-0101-2017-470-000802007