지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: To demonstrate a clinical course and feature of a female patient with a severe liver injury (DILI) during antituberculosis treatment for her intestinal tuberculosis, whom traditional Korean medicine completely recovered.
Methods: A female patient with diagnosed as DILI by antituberculosis drugs had been treated with herbal drugs; and then the clinical outcome and biochemical parameters had been monitored.
Result: A 45-year old female had taken antituberculosis drugs for about 2 months, and complained severe abdominal discomfort and dyspepsia. The RUCAM score was 10, which met the criteria for DILI (AST 584 IU/L, ALT 1212 IU/L, ALP 100 IU/L, and GGT 161 IU/L, total bilirubin 0.9 mg/dL). She had been treated with herbal drugs and acupuncture as inpatient and outpatient, and then her symptoms had been completely recovered with normalization of hepatic enzymes.
Conclusion: This report provides a clinical characteristic for a severe hepatotoxicity induced by antituberculosis drugs, and showed an example of TKM-based application.
Methods: A female patient with diagnosed as DILI by antituberculosis drugs had been treated with herbal drugs; and then the clinical outcome and biochemical parameters had been monitored.
Result: A 45-year old female had taken antituberculosis drugs for about 2 months, and complained severe abdominal discomfort and dyspepsia. The RUCAM score was 10, which met the criteria for DILI (AST 584 IU/L, ALT 1212 IU/L, ALP 100 IU/L, and GGT 161 IU/L, total bilirubin 0.9 mg/dL). She had been treated with herbal drugs and acupuncture as inpatient and outpatient, and then her symptoms had been completely recovered with normalization of hepatic enzymes.
Conclusion: This report provides a clinical characteristic for a severe hepatotoxicity induced by antituberculosis drugs, and showed an example of TKM-based application.
목차
Introduction
Report of the case
Discussion and Conclusion
References
참고문헌 (30)
참고문헌 신청
[학술지(정기간행물)] - Pandit A / 2012 / Drug-Induced Hepatotoxicity: A Review / J Appl Pharma. Science 2 (5) : 233 ~ 243
[학술지(정기간행물)] - Larson AM / 2005 / Acetaminophen-induced acute liver failure : results of a United States multicenter, prospective study / Hepatology 42 (6) : 1364 ~ 1372
[학술지(정기간행물)] - Suk KT / 2012 / Drug-induced liver injury : present and future / Clin Mol Hepatol 18 (3) : 249 ~ 257
[학술지(정기간행물)] - Meier Y / 2005 / Incidence of drug-induced liver injury in medical inpatients / Eur J Clin Pharmacol 61 (2) : 135 ~ 143
[학술지(정기간행물)] - Ghabril M / 2010 / Drug-induced liver injury : a clinical update / Curr Opin Gastroenterol 26 (3) : 222 ~ 226
[학술지(정기간행물)] - Larson AM / 2005 / Acetaminophen-induced acute liver failure : results of a United States multicenter, prospective study / Hepatology 42 (6) : 1364 ~ 1372
[학술지(정기간행물)] - Suk KT / 2012 / Drug-induced liver injury : present and future / Clin Mol Hepatol 18 (3) : 249 ~ 257
[학술지(정기간행물)] - Meier Y / 2005 / Incidence of drug-induced liver injury in medical inpatients / Eur J Clin Pharmacol 61 (2) : 135 ~ 143
[학술지(정기간행물)] - Ghabril M / 2010 / Drug-induced liver injury : a clinical update / Curr Opin Gastroenterol 26 (3) : 222 ~ 226
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UCI(KEPA) : I410-ECN-0101-2017-519-001005886