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한국미생물학회 한국미생물학회 학술대회논문집 2015년도 International Meeting of the Microbiological Society of Korea
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    초록·키워드

    Agrobacterium tumefaciens is best known for its ability to genetically modify plants through transfer and integration of a segment of DNA (T-DNA) into the plant genome, causing the disease called crown gall. Despite extensive studies of T-DNA transfer, little is known regarding the initial processes at the plant surface. A. tumefaciens forms dense biofilms on both abiotic and biotic surfaces which may increase the overall efficiency of transformation while affording protection against host defense responses. One of the primary factors mediating surface attachment in A. tumefaciens is called the unipolar polysaccharide (UPP), an adhesin produced at a single pole of the cell following surface contact. The UPP is one of several polarly localized cellular structures reported in A. tumefaciens including a tuft of unipolar flagella, and components of the Type IV secretion system (T4SS) that exports T-DNA. The cellular asymmetry is even more profoundly reflected in a polar mode of cell division for A. tumefaciens, in which cells multiply by budding and utilize a zonal mechanism of cell wall growth. Surface-attached A. tumefaciens cells generate daughter cells from their unattached pole, from which the flagella are also elaborated. The cellular asymmetry is under the control of a complex regulatory cascade designated the Control of Division and Development (CDD) pathway. Several related sensor kinases (PleC, DivJ, PdhS1, and PdhS2) and their cognate response regulators (DivK and PleD) converge on control of the CckA-ChpT-CpdR/CtrA CDD central circuit, and provide cell pole-specific modulation of division and polar development. UPP ... 전체 초록 보기

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      UCI(KEPA) : I410-ECN-0101-2017-475-001047712