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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국발육발달학회 한국발육발달학회지 한국발육발달학회지 제20권 제2호
발행연도
2012.6
수록면
89 - 94 (6page)

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초록· 키워드

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Previous studies strongly indicate that the muscle metaboreflex evokes altered cardiovascular responses to exercise in obese children. However, the effect of the mechanoreflex, another component of exercise pressor reflex (EPR), on the hemodynamic responses is not well understood. The aim of this study was to investigate the effects of the mechanoreflex on the cardiovascular responses in obese children. Twentyone subjects (8 obese and 13 lean groups, body mass index: 28.4±1.0 vs. 18.8±2.3 kg/m², respectively) participated. To stimulate the mechanoreceptors, the testing protocol involved 5 min of baseline and 1 min brief passive ankle dorsiflexion of the foot. The results showed that mean arterial pressure (MAP) increased with the mechanoreflex activation in both groups, however, the peak MAP was significantly higher in obese groups. Despite lower cardiac output (CO) response, the increase in MAP in lean groups was mainly due to lower levels of total vascular conductances (TVC). On the other hand, the higher MAP in obese groups was due to both increase in CO and decrease in TVC. There was no difference between two groups during cold pressor test. this augmented pressor response was associated with an augmented increase in both CO and peripheral vasoconstriction in obese children. These results may imply that mechanic stimuli induced by muscle contraction contribute to the overactive EPR observed in obese groups.

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UCI(KEPA) : I410-ECN-0101-2017-692-001674930