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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.10
- 수록면
- 23 - 27 (5page)
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초록· 키워드
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Background: Night shift work has well-known adverse effects on health. However, few studies have investigated the relationship between thyroid diseases and night shift work. This study aimed to examine night shift workers and their changes in thyroid stimulating hormones (TSH) levels over time.
Methods: Medical check-up data (2011–2015) were obtained from 967 female workers at a university hospital in Incheon, Korea. Data regarding TSH levels were extracted from the records, and 2015 was used as a reference point to determine night shift work status. The relationships between TSH levels and night shift work in each year were analyzed using the general linear model (GLM). The generalized estimating equation (GEE) was used to evaluate the repeated measurements over the 5-year period.
Results: The GEE analysis revealed that from 2011 to 2015, night shift workers had TSH levels that were 0.303 mIU/L higher than the levels of non-night shift workers (95 % CI: 0.087–0.519 mIU/L, p = 0.006) after adjusting for age and department. When we used TSH levels of 4.5 ≥ mIU/L to identify subclinical hypothyroidism, night shift workers exhibited a 1.399 fold higher risk of subclinical hypothyroidism (95 % CI: 1.050–1.863, p = 0.022), compared to their non-night shift counterparts.
Conclusions: This result of this study suggests that night shift workers may have an increased risk of thyroid diseases, compared to non-night shift workers.
Methods: Medical check-up data (2011–2015) were obtained from 967 female workers at a university hospital in Incheon, Korea. Data regarding TSH levels were extracted from the records, and 2015 was used as a reference point to determine night shift work status. The relationships between TSH levels and night shift work in each year were analyzed using the general linear model (GLM). The generalized estimating equation (GEE) was used to evaluate the repeated measurements over the 5-year period.
Results: The GEE analysis revealed that from 2011 to 2015, night shift workers had TSH levels that were 0.303 mIU/L higher than the levels of non-night shift workers (95 % CI: 0.087–0.519 mIU/L, p = 0.006) after adjusting for age and department. When we used TSH levels of 4.5 ≥ mIU/L to identify subclinical hypothyroidism, night shift workers exhibited a 1.399 fold higher risk of subclinical hypothyroidism (95 % CI: 1.050–1.863, p = 0.022), compared to their non-night shift counterparts.
Conclusions: This result of this study suggests that night shift workers may have an increased risk of thyroid diseases, compared to non-night shift workers.
목차
Abstract
Background
Methods
Results
Discussion
Conclusions
References
참고문헌 (27)
참고문헌 신청
Kim HJ / 2011 / Report of management for working time and shift work in Korea :19~34
Kawachi I / 1995 / Prospective study of shift work and risk of coronary heart disease in women / Circulation 92:3178~3182
Akerstedt T / 2010 / Sleep and sleepiness : impact of entering or leaving shift work-a prospective study / Chronobiol Int 27:987~996
Knutsson A / 2003 / Health disorders of shift workers / Occup Med(Lond) 53:103~108
Hansen J / 2011 / Night shift work and breast cancer risk : overall evidence / Occup Environ Med 68:236
Kawachi I / 1995 / Prospective study of shift work and risk of coronary heart disease in women / Circulation 92:3178~3182
Akerstedt T / 2010 / Sleep and sleepiness : impact of entering or leaving shift work-a prospective study / Chronobiol Int 27:987~996
Knutsson A / 2003 / Health disorders of shift workers / Occup Med(Lond) 53:103~108
Hansen J / 2011 / Night shift work and breast cancer risk : overall evidence / Occup Environ Med 68:236
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UCI(KEPA) : I410-ECN-0101-2017-517-001646258