지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.10
- 수록면
- 288 - 294 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: The aim of this work was to investigate the beneficial effects of rhamnazin against inflammation, reactive oxygen species (ROS)/reactive nitrogen species (RNS), and anti-oxidative activity in murine macrophage RAW264.7 cells. Methods: To examine the beneficial properties of rhamnazin on inflammation, ROS/ RNS, and anti-oxidative activity in the murine macrophage RAW264.7 cell model, several key markers, including COX and 5-LO activities, NO<SUP>•</SUP>, ONOO-, total reactive species formation, lipid peroxidation, <SUP>•</SUP>O₂ levels, and catalase activity were estimated. Results: Results show that rhamnazin was protective against LPS-induced cytotoxicity in macrophage cells. The underlying action of rhamnazin might be through modulation of ROS/RNS and anti-oxidative activity through regulation of total reactive species production, lipid peroxidation, catalase activity, and <SUP>•</SUP>O₂, NO<SUP>•</SUP>, and ONOO<SUP>•</SUP> levels. In addition, rhamnazin down-regulated the activities of pro-inflammatory COX and 5-LO. Conclusion: The plausible action by which rhamnazin renders its protective effects in macrophage cells is likely due to its capability to regulate LPS-induced inflammation, ROS/ RNS, and anti-oxidative activity.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
SUMMARY
REFERENCES
참고문헌 (31)
참고문헌 신청
[학술지(정기간행물)] - Kim YJ / 2010 / Attenuation of oxidative stress and inflammation by gravinol in high glucose-exposed renal tubular epithelial cells / Toxicology 270 (2-3) : 106 ~ 111
[학술지(정기간행물)] - Kim YJ / 2009 / Protection against oxidative stress, inflammation, and apoptosis of high-glucose-exposed proximal tubular epithelial cells by astaxanthin / J Agric Food Chem 57 (19) : 8793 ~ 8797
[학술지(정기간행물)] - Kim YJ / 2011 / Pycnogenol modulates apoptosis by suppressing oxidative stress and inflammation in high glucosetreated renal tubular cells / Food Chem Toxicol 49 (9) : 2196 ~ 2201
[학술지(정기간행물)] - Hofmann B / 2013 / 5-Lipoxygenase inhibitors : a review of recent patents(2010-2012) / Expert Opin Ther Pat 23 (7) : 895 ~ 909
[학술지(정기간행물)] - Koskenkorva-Frank TS / 2013 / The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress / Free Radic Biol Med 65 : 1174 ~ 1194
[학술지(정기간행물)] - Kim YJ / 2009 / Protection against oxidative stress, inflammation, and apoptosis of high-glucose-exposed proximal tubular epithelial cells by astaxanthin / J Agric Food Chem 57 (19) : 8793 ~ 8797
[학술지(정기간행물)] - Kim YJ / 2011 / Pycnogenol modulates apoptosis by suppressing oxidative stress and inflammation in high glucosetreated renal tubular cells / Food Chem Toxicol 49 (9) : 2196 ~ 2201
[학술지(정기간행물)] - Hofmann B / 2013 / 5-Lipoxygenase inhibitors : a review of recent patents(2010-2012) / Expert Opin Ther Pat 23 (7) : 895 ~ 909
[학술지(정기간행물)] - Koskenkorva-Frank TS / 2013 / The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress / Free Radic Biol Med 65 : 1174 ~ 1194
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
칵테일 용액의 종류별 라돈(222Rn) 측정결과 비교 연구
한국분석과학회 학술대회
2015 .05
-
LPS-stimulated Macrophage Activation Affects Endothelial Dysfunction
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2018 .03
-
Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages
Nutrition Research and Practice
2017 .10
-
Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages
Nutrition Research and Practice
2017 .10
-
Sonchus asper extract inhibits LPS-induced oxidative stress and pro-inflammatory cytokine production in RAW264.7 macrophages
Nutrition Research and Practice
2015 .12
-
Sonchus asper extract inhibits LPS-induced oxidative stress and pro-inflammatory cytokine production in RAW264.7 macrophages
Nutrition Research and Practice
2015 .12
-
Multiple Roles of Peroxiredoxins in Inflammation
Molecules and Cells
2016 .01
-
Anti-Inflammatory Activity of Streptomyces sp. MJ12405E in LPS-stimulated RAW 264.7 Macrophages
한국미생물학회 학술대회논문집
2017 .04
-
Anti-inflammatory effects of rutin in lipopolysaccharide-stimulated canine macrophage cells
Nutrition Research and Practice
2025 .02
-
Anti-inflammatory effects of rutin in lipopolysaccharide-stimulated canine macrophage cells
Nutrition Research and Practice
2025 .02
-
Anti-inflammatory Effects of the Ginsenosides by Regulating Inflammatory Signaling in Macrophages
한국미생물학회 학술대회논문집
2021 .08
-
Plasma and reactive oxygen species in cells
한국진공학회 학술발표회초록집
2020 .08
-
Ficus vasculosa Wall. ex Miq. Inhibits the LPS-Induced Inflammation in RAW264.7 Macrophages
한국미생물·생명공학회지
2022 .12
-
Lipopolysaccharide (LPS)-Induced Autophagy Is Responsible for Enhanced Osteoclastogenesis
Molecules and Cells
2017 .11
-
Bee Venom Decreases LPS-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells
Journal of Microbiology and Biotechnology
2017 .01
-
Anti-Inflammatory Effects of Abalone ( Haliotis discus hannai ) Viscera via Inhibition of ROS Production in LPSStimulated RAW 264.7 Cells
한국미생물·생명공학회지
2022 .03
-
Anti-inflammatory effect of enzymatic hydrolysates from Styela clava flesh tissue in lipopolysaccharide-stimulated RAW 264.7 macrophages and in vivo zebrafish model
Nutrition Research and Practice
2015 .06
-
Anti-inflammatory effect of enzymatic hydrolysates from Styela clava flesh tissue in lipopolysaccharide-stimulated RAW 264.7 macrophages and in vivo zebrafish model
Nutrition Research and Practice
2015 .06
-
RAW 264.7 대식세포에서 바위수염 메탄올 추출물에 의한 lipopolysaccharide 유도 염증성 및 산화적 스트레스의 억제
한국해양바이오학회지
2024 .12
-
Schisandrae Fructus ethanol extract attenuates particulate matter 2.5-induced inflammatory and oxidative responses by blocking the activation of the ROS-dependent NF-κB signaling pathway
Nutrition Research and Practice
2021 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2017-594-001640157