지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 233 - 238 (6page)
이용수
초록· 키워드
오류제보하기
Xylene is a cyclic hydrocarbon and an environmental pollutant. It is also used in medical technology, paints, dyes, polishes and in many industries as a solvent; therefore, an understanding of the interaction between xylene and human lymphocytes is of significant interest. Biochemical assessment was used to demonstrate that exposure of lymphocytes to xylene induces cytotoxicity (at 6 hr), generates intracellular reactive oxygen species, collapse of mitochondrial membrane potential, lysosomal injury, lipid peroxidation and depletion of glutathione (at 3 hr). The findings show that xylene triggers oxidative stress and organelle damage in lymphocytes. The results of our study suggest that the use of antioxidant, mitochondrial and lysosomal protective agents can be helpful for individuals subject to chronic exposure to xylene.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGMENTS
REFERENCES
참고문헌 (26)
참고문헌 신청
Niaz, K / 2015 / A review of environmental and occupational exposure to xylene and its health concerns / EXCLI J 14:1167~1186
Langman, J.M / 1994 / Xylene: its toxicity, measurement of exposure levels, absorption, metabolism and clearance / Pathology 26:301~309
Substances, A.f.T / 2007 / Toxicological profile for xylene, US Department of Health and Human Services / US Public Health Service, Agency for Toxic Substances and Disease Registry Atlanta
Šedivec, V / 1976 / Exposure test for xylenes / Int. Arch. Occup. Environ. Health 37:219~232
Ogata, M / 1971 / Excretion of hippuric acid and m- or p-methylhippuric acid in the urine of persons exposed to vapours of toluene and m- or p-xylene in an exposure chamber and in workshops, with specific reference to repeated exposures / Br. J. Ind. Med 28:382~385
Langman, J.M / 1994 / Xylene: its toxicity, measurement of exposure levels, absorption, metabolism and clearance / Pathology 26:301~309
Substances, A.f.T / 2007 / Toxicological profile for xylene, US Department of Health and Human Services / US Public Health Service, Agency for Toxic Substances and Disease Registry Atlanta
Šedivec, V / 1976 / Exposure test for xylenes / Int. Arch. Occup. Environ. Health 37:219~232
Ogata, M / 1971 / Excretion of hippuric acid and m- or p-methylhippuric acid in the urine of persons exposed to vapours of toluene and m- or p-xylene in an exposure chamber and in workshops, with specific reference to repeated exposures / Br. J. Ind. Med 28:382~385
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UCI(KEPA) : I410-ECN-0101-2018-513-001055202