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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.22 No.4
- 발행연도
- 2017.12
- 수록면
- 312 - 319 (8page)
- DOI
- 10.3746/pnf.2017.22.4.312
이용수
초록· 키워드
오류제보하기
Rhizoid of Laminaria japonica was hydrolyzed with proteases and carbohydrases to obtain antioxidant materials. Oxygen radical absorbance capacity (ORAC) of the enzymatic extracts was evaluated and the Protamex extract (PE) exhibited the highest ORAC value. PE also potently scavenged 2,2-diphenyl-1-picrylhydrazyl radical, 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic) acid cation radical, and hydrogen peroxide (H2O2) and had good reducing power. PE inhibited hydroxyl radical-induced DNA scission by measuring the conversion of supercoiled pBR322 plasmid DNA to the open circular form. The cytoprotective effect of PE against H2O2-induced hepatic cell damage was also investigated. PE showed a dose-dependent cytoprotective effect in cultured hepatocytes by inhibiting intracellular reactive oxygen species scavenging activity. In addition, PE up-regulated the expression of heme oxygenase-1, which is a cytoprotective enzyme, by activating translocation of nuclear factor-erythroid 2-related factor 2. Taken together, the enzymatic extract of rhizoid of L. japonica, particularly PE, may be useful for antioxidant additives.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (44)
참고문헌 신청
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Aruoma OI. 1994. Nutrition and health aspects of free radicals and antioxidants. Food Chem Toxicol 32: 671-683.
Samaranayaka AGP, Li-Chan ECY. 2011. Food-derived peptidic antioxidants: a review of their production, assessment, and potential applications. J Funct Foods 3: 229-254.
Liu M, Liu Y, Cao MJ, Liu GM, Chen Q, Sun L, Chen H. 2017. Antibacterial activity and mechanisms of depolymerized fucoidans isolated from Laminaria japonica. Carbohydr Polym 172: 294-305.
Victor Lin HT, Lu WJ, Tsai GJ, Chou CT, Hsiao HI, Hwang PA. 2016. Enhanced anti-inflammatory activity of brown seaweed Laminaria japonica by fermentation using Bacillus subtilis. Proc Biochem 51: 1945-1953.
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UCI(KEPA) : I410-ECN-0101-2018-594-001729180