지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.94 No.2
- 발행연도
- 2018.2
- 수록면
- 69 - 73 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: The availability of intraoperative parathyroid hormone (IOPTH) monitoring allows successful focused parathyroidectomy for primary hyperparathyroidism (pHPT). The objective of this study was to report our initial experience in IOPTH monitoring during parathyroid surgery for primary hyperparathyroidsim.
Methods: Between May 2011 and February 2013, 37 patients underwent focused parathyroidectomy due to pHPT. IOPTH monitoring based on Miami criteria was used to confirm complete excision of hyperfunctioning parathyroid gland during surgery. Medical records of patients were reviewed retrospectively.
Results: Preoperative mean maximal calcium level was 11.7 ± 0.9 mg/dL. Preoperative technetium (<SUP>99m</SUP>Tc) sestamibi scan and ultrasonography identified 32 of 37 (86.5%) and 29 of 37 (78.4%) of abnormal parathyroid glands, retrospectively. Results of the 2 imaging modalities were discordant for 8 cases (21.6%). The mean pre-excision PTH level was 147.2 ± 201.5 pg/mL. At 5- and 10-minute post tumor resection, PTH levels were 65.3 ± 25.4 pg/mL and 47.5 ± 24.3 pg/mL, respectively. In all cases, IOPTH levels fell by at least 50% after removing all suspected abnormal glands. All patients had a successful return to normocalcemia after surgery (mean follow-up period: 60.2 ± 15.4 months).
Conclusion: Surgeon could confirm complete excision of abnormal hyperfunctioning parathyroid glands by IOPTH monitoring during surgery for pHPT. IOPTH monitoring can maximize performance of successful focused parathyroidectomy for pHPT, especially when preoperative imaging results are discordant.
Methods: Between May 2011 and February 2013, 37 patients underwent focused parathyroidectomy due to pHPT. IOPTH monitoring based on Miami criteria was used to confirm complete excision of hyperfunctioning parathyroid gland during surgery. Medical records of patients were reviewed retrospectively.
Results: Preoperative mean maximal calcium level was 11.7 ± 0.9 mg/dL. Preoperative technetium (<SUP>99m</SUP>Tc) sestamibi scan and ultrasonography identified 32 of 37 (86.5%) and 29 of 37 (78.4%) of abnormal parathyroid glands, retrospectively. Results of the 2 imaging modalities were discordant for 8 cases (21.6%). The mean pre-excision PTH level was 147.2 ± 201.5 pg/mL. At 5- and 10-minute post tumor resection, PTH levels were 65.3 ± 25.4 pg/mL and 47.5 ± 24.3 pg/mL, respectively. In all cases, IOPTH levels fell by at least 50% after removing all suspected abnormal glands. All patients had a successful return to normocalcemia after surgery (mean follow-up period: 60.2 ± 15.4 months).
Conclusion: Surgeon could confirm complete excision of abnormal hyperfunctioning parathyroid glands by IOPTH monitoring during surgery for pHPT. IOPTH monitoring can maximize performance of successful focused parathyroidectomy for pHPT, especially when preoperative imaging results are discordant.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (28)
참고문헌 신청
[학술지(정기간행물)] - Gil-Cardenas A / 2007 / Is intraoperative parathyroid hormone assay manda tory for the success of targeted para thyroidectomy? / J Am Coll Surg 204 : 286 ~ 290
[학술지(정기간행물)] - Cayo AK / 2009 / Utility of intraoperative PTH for primary hyperparathyroidism due to multigland disease / Ann Surg Oncol 16 : 3450 ~ 3454
[학술지(정기간행물)] - Miccoli P / 2004 / Results of videoassisted parathyroidectomy: single institu tion's six-year experience / World J Surg 28 : 1216 ~ 1218
[학술지(정기간행물)] - Grant CS / 2005 / Primary hyperparathyroidism sur gical management since the introduc tion of minimally invasive para thyroidectomy: Mayo Clinic experience / Arch Surg 140 : 472 ~ 478
[학술지(정기간행물)] - Bergenfelz AO / 2009 / Impact of modern techniques on short-term outcome after surgery for primary hyperparathyroidism: a multicenter study comprising 2,708 patients / Langenbecks Arch Surg 394 : 851 ~ 860
[학술지(정기간행물)] - Cayo AK / 2009 / Utility of intraoperative PTH for primary hyperparathyroidism due to multigland disease / Ann Surg Oncol 16 : 3450 ~ 3454
[학술지(정기간행물)] - Miccoli P / 2004 / Results of videoassisted parathyroidectomy: single institu tion's six-year experience / World J Surg 28 : 1216 ~ 1218
[학술지(정기간행물)] - Grant CS / 2005 / Primary hyperparathyroidism sur gical management since the introduc tion of minimally invasive para thyroidectomy: Mayo Clinic experience / Arch Surg 140 : 472 ~ 478
[학술지(정기간행물)] - Bergenfelz AO / 2009 / Impact of modern techniques on short-term outcome after surgery for primary hyperparathyroidism: a multicenter study comprising 2,708 patients / Langenbecks Arch Surg 394 : 851 ~ 860
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