지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.94 No.3
- 발행연도
- 2018.3
- 수록면
- 129 - 134 (6page)
이용수
이 논문의 연구 히스토리 (2)
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Purpose: Although few hepatectomy patients develop unexpected early diffuse and multinodular recurrence in the remnant liver, the prognosis in such cases is often dismal. The aim of this study was to evaluate the risk factors of early disseminated multinodular hepatocellular carcinoma (HCC) recurrence within 3 months after liver resection for solitary HCC.
Methods: Eighty-four patients who were diagnosed with recurrent HCC within 3 months after hepatectomy for solitary HCC were retrospectively reviewed. Disseminated HCC recurrence was defined as more than 10 tumors in both lobes and total tumor size >10 cm.
Results: Preoperative α-FP level, incidence of poor tumor grade, and presence of portal vein tumor thrombosis were higher in the patients with disseminated HCC recurrence than in those without disseminated HCC recurrence (P < 0.05). Multivariate analysis showed that α-FP >1,000 ng/dL was a predisposing factor of disseminated HCC recurrence within 3 months after liver resection. The overall survival rate for patients without disseminated HCC recurrence was higher than that for patients with disseminated HCC recurrence (P < 0.001).
Conclusion: Early disseminated multinodular HCC recurrence in hepatectomy patients was associated with preoperative α-FP >1,000 ng/dL. Such patients should be frequently evaluated for the early detection of recurrent HCC for early intervention.
Methods: Eighty-four patients who were diagnosed with recurrent HCC within 3 months after hepatectomy for solitary HCC were retrospectively reviewed. Disseminated HCC recurrence was defined as more than 10 tumors in both lobes and total tumor size >10 cm.
Results: Preoperative α-FP level, incidence of poor tumor grade, and presence of portal vein tumor thrombosis were higher in the patients with disseminated HCC recurrence than in those without disseminated HCC recurrence (P < 0.05). Multivariate analysis showed that α-FP >1,000 ng/dL was a predisposing factor of disseminated HCC recurrence within 3 months after liver resection. The overall survival rate for patients without disseminated HCC recurrence was higher than that for patients with disseminated HCC recurrence (P < 0.001).
Conclusion: Early disseminated multinodular HCC recurrence in hepatectomy patients was associated with preoperative α-FP >1,000 ng/dL. Such patients should be frequently evaluated for the early detection of recurrent HCC for early intervention.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (17)
참고문헌 신청
[학술지(정기간행물)] - Cherqui D / 2009 / Liver resection for transplantable hepatocellular carcinoma: long-term survival and role of secondary liver transplantation / Ann Surg 250 : 738 ~ 746
[학술지(정기간행물)] - Lee HY / 2013 / Early diffuse recurrence of hepatocellular carcinoma after percutaneous radiofrequency ablation: analysis of risk factors / Eur Radiol 23 : 190 ~ 197
[학술지(정기간행물)] - Kim JM / 2014 / Outcomes after curative hepatectomy in patients with non-B non-C hepatocellular carcinoma and hepatitis B virus hepatocellular carcinoma from non-cirrhotic liver / J Surg Oncol 110 : 976 ~ 981
[학술지(정기간행물)] - Kim JM / 2014 / Differences between hepatocellular carcinoma and hepatitis B virus infection in patients with and without cirrhosis / Ann Surg Oncol 21 : 458 ~ 465
[학술지(정기간행물)] - Imamura H / 2003 / Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy / J Hepatol 38 : 200 ~ 207
[학술지(정기간행물)] - Lee HY / 2013 / Early diffuse recurrence of hepatocellular carcinoma after percutaneous radiofrequency ablation: analysis of risk factors / Eur Radiol 23 : 190 ~ 197
[학술지(정기간행물)] - Kim JM / 2014 / Outcomes after curative hepatectomy in patients with non-B non-C hepatocellular carcinoma and hepatitis B virus hepatocellular carcinoma from non-cirrhotic liver / J Surg Oncol 110 : 976 ~ 981
[학술지(정기간행물)] - Kim JM / 2014 / Differences between hepatocellular carcinoma and hepatitis B virus infection in patients with and without cirrhosis / Ann Surg Oncol 21 : 458 ~ 465
[학술지(정기간행물)] - Imamura H / 2003 / Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy / J Hepatol 38 : 200 ~ 207
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Validation for models for tumor recurrence after liver transplantation in hepatectomy patients
Annals of Surgical Treatment and Research
2022 .03
-
Substantial risk of recurrence even after 5 recurrence-free years in early-stage hepatocellular carcinoma patients
Clinical and Molecular Hepatology
2020 .01
-
Independent Risk Factors for Hepatocellular Carcinoma Recurrence after Direct-Acting Antiviral Therapy in Patients with Chronic Hepatitis C
Gut and Liver
2021 .01
-
Protrusion of hepatocellular carcinoma is a predictor of early recurrence in hepatectomy patients after spontaneous rupture
Annals of Surgical Treatment and Research
2016 .06
-
Change in the Recurrence Pattern and Predictors over Time after Complete Cure of Hepatocellular Carcinoma
Gut and Liver
2021 .01
-
Prediction models of hepatocellular carcinoma recurrence after liver transplantation: A comprehensive review
Clinical and Molecular Hepatology
2022 .10
-
Outcomes of Living Donor Liver Transplantation in Patients with a History of Ruptured Hepatocellular Carcinoma
대한외과학회 학술대회 초록집
2021 .05
-
단일 거대 간세포암의 수술적 절제 후 급격히 다발성 간외 전이가 진행된1예
Journal of Liver Cancer
2016 .01
-
Liver Transplantation in Mixed Hepatocellular Carcinoma and Cholangiocarcinoma
Journal of Liver Cancer
2019 .01
-
A comparison of the risk factors of intrahepatic recurrence, early recurrencen, and multiple recurrences after resection for single nodular hepatocellular carcinoma
Annals of Hepato-Biliary-Pancreatic Surgery
2015 .08
-
Is the anatomical resection necessary for single hepatocellular carcinoma smaller than 3 cm? : single-center experience of liver resection for a small HCC
Annals of Hepato-Biliary-Pancreatic Surgery
2018 .11
-
Appropriate treatment modality for solitary small hepatocellular carcinoma: Radiofrequency ablation vs. resection vs. transplantation?
Clinical and Molecular Hepatology
2019 .01
-
환자표본자료를 이용한 간세포암종 환자의 의료이용 특성 및 치료별 의료비용 분석
한국임상약학회지
2021 .01
-
Prognosis of Spontaneous Bacterial Peritonitis in Hepatocellular Carcinoma Patients
Journal of Korean Medical Science
2018 .01
-
Health-Related Quality of Life of Patients with Intermediate Hepatocellular Carcinoma after Liver Resection or Transcatheter Arterial Chemoembolization
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Advances in Management of Hepatocellular Carcinoma
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Current Trends and Recent Advances in Diagnosis, Therapy, and Prevention of Hepatocellular Carcinoma
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Blood Neutrophil-to-Lymphocyte Ratio Predicts Tumor Recurrence in Patients with Hepatocellular Carcinoma within Milan Criteria after Hepatectomy
Yonsei Medical Journal
2016 .01
-
Long-term outcomes of liver resection for multiple hepatocellular carcinomas: Single-institution experience with 187 patients
Annals of Hepato-Biliary-Pancreatic Surgery
2020 .11
-
Prognosis after intrahepatic recurrence in the patients who underwent curative resection for hepatocellular carcinoma
Annals of Hepato-Biliary-Pancreatic Surgery
2020 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-514-001804873