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논문 기본 정보

자료유형
학술저널
저자정보
(National Nutrition and Food Technology Research Institute) (Research Institute for Endocrine Sciences) (Research Institute for Endocrine Sciences) (Research Institute for Endocrine Sciences) (Shahid Beheshti University of Medical Sciences)
저널정보
한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.23 No.2
발행연도
수록면
87 - 93 (7page)
DOI
10.3746/pnf.2018.23.2.87

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초록· 키워드

The aim of this study was to explore the association of dietary sodium to potassium (Na/K) ratio and the risk of chronic kidney disease (CKD) in general Iranian adults. In this prospective cohort study, 1,780 adults, free of baseline CKD with complete follow-up data, were selected from among participants of the Tehran Lipid and Glucose Study and followed for 6.3 years for development of CKD. Dietary sodium and potassium were assessed using a valid and reliable 168-item food frequency questionnaire. Estimated glomerular filtration rate (eGFR) was calculated using the Modification of Diet in Renal Disease Study equation, and CKD was defined as eGFR <60 mL/min/1.73 ㎡. Mean dietary intakes of sodium and potassium were 4,547±3,703 and 3,753±1,485 mg/d, respectively, and their ratio was 1.35±1.29. No significant association was found between dietary intakes of sodium and potassium and the risk of CKD after 6.3 y of followup, whereas in the case of dietary Na/K ratio, participants in the highest compared to lowest tertile (2.43 vs 1.61) had a significantly increased risk of CKD (odds ratio＝1.52, 95% confidence interval＝1.01∼2.30); an increasing trend in the risk of CKD across tertiles of dietary sodium to potassium ratio was also observed (P for trend＝0.05). Present findings demonstrate that the dietary Na/K ratio is a stronger predictor of CKD than the dietary sodium or potassium per se. Decreased dietary Na/K ratio may be considered as an effective dietary approach to modify the risk of kidney dysfunction.
#dietary sodium #dietary potassium #sodium to potassium ratio #chronic kidney disease
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목차

  1. ABSTRACT
  2. INTRODUCTION
  3. MATERIALS AND METHODS
  4. RESULTS
  5. DISCUSSION
  6. REFERENCES

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UCI(KEPA) : I410-ECN-0101-2018-594-003146167