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논문 기본 정보

자료유형
학술저널
저자정보
Judith Sharmila (Chonbuk National University) Adithan Aravinthan (Chonbuk National University) Dong Gue Shin (GeneralBio) Jeong Hun Seo (GeneralBio) Bumseok Kim (Chonbuk National University) Nam Soo Kim (Chonbuk National University) Chang-Won Kang (Chonbuk National University) Jong-Hoon Kim (Chonbuk National University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.42 No.3
발행연도
2018.6
수록면
356 - 360 (5page)

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The fermentation of medicinal herbs facilitated by microbes is assumed to exert promising therapeutic efficacy on the absorption, bioavailability, and pharmacological effects by speeding up the making or conversion of active constituents into their metabolites. We examined the cardioprotective potential of fermented ginseng, GBCK25, against high-fat diet (HFD)-induced metabolic and functional illnesses as following the essential analysis such as electrocardiographic parameters, alterations of body and organ weights, and echocardiographic studies. The results exhibited that body weights were significantly reduced and the gain of different organ weights were partly eased by GBCK25 treatment. Echocardiography results proposed the amelioration of heart function through normalized levels of left ventricle systolic pressure, ejection fraction, and fractional shortening. These outcomes deliver straight confirmation that GBCK25 could be a potential nutraceutical source for the relief of HFD-induced obesity mediated cardiac dysfunctions.

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UCI(KEPA) : I410-ECN-0101-2018-524-003161246