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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.11
- 수록면
- 495 - 505 (11page)
- DOI
- 10.7856/kjcls.2018.29.4.495
이용수
초록· 키워드
오류제보하기
This study compared the cholesterol lowering effects of loquat leaf and the fruit ethanol extracts on rats fed a high-cholesterol diet. Male Sprague-Dawley rats were divided into 4 groups: normal diet group (ND), high-cholesterol diet group (HCD), high-cholesterol diet and loquat leaf with 400 mg/kg treated group (HCD-LLE), and high-cholesterol diet and loquat fruit with 400 mg/kg treated group (HCD-LFE). No significant differences were found in body weight gain, food intake, adipose tissue weight, serum LDH activities, triglyceride (TG), and hepatic and fecal total lipid contents in both the normal (ND) and high-cholesterol diet fed groups (HCD, HCD-LLE, HCD-LFE). The serum ALT, AST and ALP activities, total cholesterol (TC), LDL-cholesterol, atherogenic index, cardiac risk factor, and hepatic TC contents were significantly lower in the HCD-LLE and HCD-LFE groups, whereas the HCD-LLE group showed a significantly higher serum HLD-cholesterol, and fecal TC and total bile acid content than the HCD and HCD-LLE groups. The cholesterol-lowering effects were greater in the HCD-LLE group than in the HCD-LFE group. These results suggest that loquat ethanol extracts may improve the serum and hepatic lipid profiles, and enhance the fecal excretion of lipids in mice fed a high-cholesterol diet.
목차
ABSTRACT
I. 서론
Ⅱ. 연구방법
Ⅲ. 결과 및 고찰
Ⅳ. 요약 및 결론
References
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UCI(KEPA) : I410-ECN-0101-2019-590-000163357