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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.8
- 수록면
- 217 - 226 (10page)
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The study was conducted to investigate candidate materials as anti-inflammation agent from plant resources. Activities of 33 plant parts extracts with the final concentration of 5㎍/㎖ were evaluated on the several inflammationrelated markers such as the release of proinflammatoty cytokine [tumor necrosis factor-alpha (TNF-α) & interleukin-6 (IL-6)], nitric oxide (NO), the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and inhibitor of nuclear factor kappa-B alpha (Iκ-Bα) in lipopolysaccharide (LPS)-treated RAW 264.7 cells. The extracts in the final concentration of 10 ㎍/㎖ were also screened on peroxynitrite (ONOO￣) scavenging activity. Eleven extracts selected from the screening assay were verified on the inhibition activity on peroxynitrite and total reactive species oxygen (ROS) in the several concentrations. As results, Alpinia officinarum Hance (rhizome), Inula britannica var. chinensis Regel (flower), Ulmus arvifolia Jacq (trunk peel) and Aster scaber Thunb. (aerial part) showed comparatively potent anti-inflammatory activities in vitro cells or chemical level systems, and then these four plant parts should be studied on the antiinflammatory mechanism by further studies.
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참고문헌 (18)
참고문헌 신청
Beckman JS / 1994 / Pathological implications of nitric oxide, superoxide and peroxynitrite formation / Biochemical Society Transactions 21:330~334
Finotto S / 1994 / TNF-alpha production by eosinophiles in upper airways inflammation (nasal polyposis) / Journal of Immunology 153:2278~2289
정용준 / 2009 / 상황버섯과 발아현미상황버섯 열수추출물의 Murin Macrophage RAW 264.7 세포에서 항염증 반응 비교 / 한국약용작물학회지 17(2):97~101
Hendel J / 1997 / Expression of cyclooxygenase- 2 mRNA in active inflammatory bowel disease / American Journal of Gastroenterology 392:1170~1173
Kaplanski G / 2003 / IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation / Trends in Immunology 24:25~29
Finotto S / 1994 / TNF-alpha production by eosinophiles in upper airways inflammation (nasal polyposis) / Journal of Immunology 153:2278~2289
정용준 / 2009 / 상황버섯과 발아현미상황버섯 열수추출물의 Murin Macrophage RAW 264.7 세포에서 항염증 반응 비교 / 한국약용작물학회지 17(2):97~101
Hendel J / 1997 / Expression of cyclooxygenase- 2 mRNA in active inflammatory bowel disease / American Journal of Gastroenterology 392:1170~1173
Kaplanski G / 2003 / IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation / Trends in Immunology 24:25~29
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UCI(KEPA) : I410-ECN-0101-2019-480-000588302