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(금산국제인삼약초연구소) (금산국제인삼약초연구소) (금산국제인삼약초연구소) (금산국제인삼약초연구소) (금산국제인삼약초연구소) (금산국제인삼약초연구소)
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한국약용작물학회 한국약용작물학회 학술대회논문집 한국약용작물학회 2018년도 춘계학술발표회
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    초록·키워드

    Non-alcoholic fatty liver disease (NAFLD) is caused by obesity, type 2 diabetes mellitus, dyslipidemia, and genetic factors. Also, hyperinsulinemia directly promotes fat accumulation in hepatocytes. Therefore, it is very important to suppress the most common risks of NAFLD, such as obesity and insulin resistance. In this context, we evaluated for the effects of black ginseng (BG) extract on lipid accumulation inhibition and degradation in hepatocytes. The aim of this study is to figure out the potential anti-lipogenic effects and the underlying mechanism of BG extract in a cellular-, type 2 diabetes mellitus (T2DM) animal model associated with NAFLD. T2DM animal used C57BL/KsJ db/db mouse (M. 6 wk, n = 56), treated with extract of BG and Red ginseng (RG) (each 100 and 900 mg/kg/day, p.o) for 6 weeks. BG markedly reduced palmitate-induced intracellular lipid accumulation in HepG2 cells. On histology of liver tissues of T ... 전체 초록 보기

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      UCI(KEPA) : I410-ECN-0101-2019-480-000615864