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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Patients with severe stroke due to acute large cerebral artery occlusion are likely to be severely disabled or dead without timely reperfusion. Previously, intravenous tissue plasminogen activator (IV-TPA) within 4.5 hours after stroke onset was the only proven therapy, but IV-TPA alone does not sufficiently improve the outcome of patients with acute large artery occlusion. With the introduction of the advanced endovascular therapy, which enables more fast and more successful recanalization, recent randomized trials consecutively and consistently demonstrated the benefit of endovascular recanalization therapy (ERT) when added to IV-TPA. Accordingly, to update the recommendations, we assembled members of the writing committee appointed by the Korean Stroke Society, the Korean Society of Interventional Neuroradiology, and the Society of Korean Endovascular Neurosurgeons. Reviewing the evidences that have been accumulated, the writing members revised recommendations, for which formal consensus was achieved by convening a panel composed of 34 experts from the participating academic societies. The current guideline provides the evidence-based recommendations for ERT in patients with acute large cerebral artery occlusion regarding patient selection, treatment modalities, neuroimaging evaluation, and system organization.
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참고문헌 (42)
참고문헌 신청
The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group / 1995 / Tissue plasminogen activator for acute ischemic stroke / N Engl J Med 333:1581~1587
Hacke W / 2008 / Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke / N Engl J Med 359:1317~1329
Emberson J / 2014 / Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials / Lancet 384:1929~1935
Furlan A / 1999 / Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism / JAMA 282:2003~2011
Lee M / 2010 / Efficacy of intra-arterial fibrinolysis for acute ischemic stroke : meta-analysis of randomized controlled trials / Stroke 41:932~937
Hacke W / 2008 / Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke / N Engl J Med 359:1317~1329
Emberson J / 2014 / Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials / Lancet 384:1929~1935
Furlan A / 1999 / Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism / JAMA 282:2003~2011
Lee M / 2010 / Efficacy of intra-arterial fibrinolysis for acute ischemic stroke : meta-analysis of randomized controlled trials / Stroke 41:932~937
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