지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Early evaluation of the pyramidal tract using Diffusion Tensor Imaging (DTI) is a prerequisite to decide the optimal treatment or to assess appropriate rehabilitation. The early predictive value of DTI for assessing motor and functional recovery in ischemic stroke (IS) has yielded contradictory results. The purpose is to systematically review and summarize the current available literature on the value of Fractional Anisotropy (FA) parameter of the DTI in predicting upper limb motor recovery after sub-acute IS. MEDLINE, PubMed, EMBASE, Google Scholar and Cochrane CENTRAL searches were conducted from January 1, 1950, to July 31, 2015, which was supplemented with relevant articles identified in the references. Correlation between FA and upper limb motor recovery measure was done. Heterogeneity was examined using Higgins I-squared, Tau-squared. Summary of correlation coefficient was determined using Random Effects model. Out of 166 citations, only eleven studies met the criteria for inclusion in the systematic review and six studies were included in the meta-analysis. A random effects model revealed that DTI parameter FA is a significant predictor for upper limb motor recovery after sub-acute IS [Correlation Coefficient=0.82; 95% Confidence Interval-0.66 to 0.90, P value<0.001]. Moderate heterogeneity was observed (Tau-squared=0.12, I-squared=62.14). The studies reported so far on correlation between DTI and upper limb motor recovery are few with small sample sizes. This meta-analysis suggests strong correlation between DTI parameter FA and upper limb motor recovery. Well-designed prospective trials embedded with larger sample size are required to establish these findings.
목차
등록된 정보가 없습니다.
참고문헌 (42)
참고문헌 신청
Feigin VL / 2014 / Global and regional burden of stroke during 1990-2010 : findings from the Global Burden of Disease Study 2010 / Lancet 383:245~254
Hendricks HT / 2002 / Motor recovery after stroke : a systematic review of the literature / Arch Phys Med Rehabil 83:1629~1637
Hankey GJ / 2005 / Preventable stroke and stroke prevention / J Thromb Haemost 3:1638~1645
de Weerdt W / 1987 / Prediction of arm and hand function recovery in stroke patients / Int J Rehabil Res 10(4 Suppl 5):110~112
Vora NA / 2011 / A 5-item scale to predict stroke outcome after cortical middle cerebral artery territory infarction : validation from results of the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution(DEFUSE)Study / Stroke 42:645~649
Hendricks HT / 2002 / Motor recovery after stroke : a systematic review of the literature / Arch Phys Med Rehabil 83:1629~1637
Hankey GJ / 2005 / Preventable stroke and stroke prevention / J Thromb Haemost 3:1638~1645
de Weerdt W / 1987 / Prediction of arm and hand function recovery in stroke patients / Int J Rehabil Res 10(4 Suppl 5):110~112
Vora NA / 2011 / A 5-item scale to predict stroke outcome after cortical middle cerebral artery territory infarction : validation from results of the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution(DEFUSE)Study / Stroke 42:645~649
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