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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1 - 15 (15page)
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초록· 키워드
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Objectives In the theory of Korean Medicine, Cicadae Periostracum (CP) has been used to treat skin diseases such as inflammatory dermatitis, tetanus and pruritus. CP can reduce heat and disperse wind. In prior studies, anti-allergic effect and anti-inflammatory effect of CP were reported. However, there has been no report regarding the correlation of CP and allergic contact dermatitis (ACD). This study was performed to show the effects of CP in ACD induced by 2,4-dinitrochlorobenzene (DNCB) in mice.
Methods In this experiment, the effects of CP on biological changes were measured, such as changes in ear and spleen weight, ear and dorsum skin thickness, clinical aspect on the dorsum skin and histological changes.
The effect of proliferation rate of splenocytes was also investigated in vitro and vivo study.
Results In results, CP application (CPA) group and CP application and administration (CPAA) group were significantly restrained in ear weight gain and increase in ear and dorsum skin thickness compared to the control group. In addition, CPA and CPAA group showed diminished erythema, desquamation, bloodstain, and marks. Also, the histological assessment showed that CP treatement diminished thickness of epidermis, hyperkeratosis, pigmentation and parakeratosis.
Conclusions In conclusion, these data suggest that CP can decrease symptoms of ACD.
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등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Cho SW / 2001 / Effects of
Chonnam National University Graduate Medical School Allergy / 2013 / Allergy & clinical immunology / Chonnam National Univ Press : 43 ~ 44
Dam SH / 2001 / Jungeuioekwahak / InMinWiSaeng Publishing Co : 755 ~ 756
Hanuigwadaehak Bonchohak Pyeonchanwiwonhoe / 2011 / Bonchohak / YeongRimSa Publising Co : 195 ~ 197
Heo H / 2007 / A practical guide to 60 skin diseases / UUP : 137 ~ 139
Chonnam National University Graduate Medical School Allergy / 2013 / Allergy & clinical immunology / Chonnam National Univ Press : 43 ~ 44
Dam SH / 2001 / Jungeuioekwahak / InMinWiSaeng Publishing Co : 755 ~ 756
Hanuigwadaehak Bonchohak Pyeonchanwiwonhoe / 2011 / Bonchohak / YeongRimSa Publising Co : 195 ~ 197
Heo H / 2007 / A practical guide to 60 skin diseases / UUP : 137 ~ 139
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