지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 2 - 10 (9page)
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초록· 키워드
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Background: Probiotics are currently under focus for their immune improvement function. Many studies have been performed to assess the potential efficacy of probiotics in allergic disease, viral disease, respiratory disease, as well as gastrointestinal disease. This study performed a systematic review to determine the effects of probiotics on the prevention of the common cold.
Methods: We searched MEDLINE (PubMed), EMBASE, CINAHL, and Cochrane CENTRAL for studies released through June 2011. Two authors independently extracted the data. To assess the risk of bias of included literatures, Cochrane Collaboration’s risk of bias tool was used.
Results: We identified 10 studies in 7 articles. A total 2,894 participants, 1,588 in the probiotics group and 1,306 in the control group, were included. The effect of probiotics on the prevention of the common cold had a relative risk (RR) of 0.92(95% CI, 0.85 to 1.00, I2 = 26%). In the subgroup analysis, the RR of administration of probiotics for 3 months or less was 0.82 (95% CI, 0.70 to 0.97). The RR of administration of probiotics over 3 months was 1.00 (95% CI, 0.92 to 1.09). The RR of administration of probiotics without any active intervention (vitamin and mineral) was 0.87 (95% CI, 0.78 to 0.97).
Conclusion: In this meta-analysis, there was marginal effect of probiotics on the prevention of the common cold. The results implied that probiotics had a modest effect in common cold reduction. The balance of benefit and harms needs to be considered when using probiotics for common cold prevention.
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참고문헌 (19)
참고문헌 신청
/ 2011 / Review Manager / The Nordic Cochrane Centre
Alfaleh K / 2011 / Probiotics for prevention of necrotizing enterocolitis in preterm infants / Cochrane Database Syst Rev (3) : CD005496 ~
Douglas RM / 2007 / Vitamin C for preventing and treating the common cold / Cochrane Database Syst Rev (3) : CD000980 ~
Feldman S / 2009 / Randomized phase II clinical trials of Wellmune WGP for immune support during cold and flu season / J Appl Res 9 : 30 ~ 42
Guillemard E / 2010 / Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114001 reduces the duration of respiratory infections in the e
Alfaleh K / 2011 / Probiotics for prevention of necrotizing enterocolitis in preterm infants / Cochrane Database Syst Rev (3) : CD005496 ~
Douglas RM / 2007 / Vitamin C for preventing and treating the common cold / Cochrane Database Syst Rev (3) : CD000980 ~
Feldman S / 2009 / Randomized phase II clinical trials of Wellmune WGP for immune support during cold and flu season / J Appl Res 9 : 30 ~ 42
Guillemard E / 2010 / Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114001 reduces the duration of respiratory infections in the e
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