지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 80 - 89 (10page)
이용수
초록· 키워드
오류제보하기
Background: Lactobacillus gasseri BNR17 is a type of probiotic strain isolated from human breast milk. A study was reported regarding the fact that BNR17 was an inhibitor of obesity and diabetic activities in the human body through previous animal experiments. This study was furthered to investigate the effect of BNR17, a probiotic strain isolated from human breast milk, on obese and overweight adults.
Methods: Sixty-two obese volunteers aged 19 to 60 with body mass index ≥ 23 kg/m2 and fasting blood sugar ≥ 100 mg/dL participated in a placebo controlled, randomized, and double-blind trial. For 12 weeks, 57 participants were given either placebo or BNR17 and were tested by measuring body fat, body weight, various biochemical parameters, vital signs, and computed tomography at the start of the study and at weeks 4, 8, and 12. The subjects assumed usual daily activities without having to make behavioral or dietary modifications during the course of the study.
Results: At the 12th week, a slight reduction in body weight was noted in the BNR17 group, but there were no significant weight changes between groups. Decrease of waist and hip circumferences in the BNR17 group was more pronounced than those in the placebo group. The two groups had no special or severe adverse reactions.
Conclusion: Despite there being no change in behavior or diet, administration of only the supplement of BNR17 reduced weight and waist and hip circumference. However, there were no significant differences between the two groups. These findings warrant a subsequent longer-term prospective clinical investigation with a large population.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Agerbaek M / 1995 / Hypocholesterolaemic effect of a new fermented milk product in healthy middleaged men / Eur J Clin Nutr 49 : 346 ~ 352
Backhed F / 2004 / The gut microbiota as an environmental factor that regulates fat storage / Proc Natl Acad Sci U S A 101 : 15718 ~ 15723
Cani PD / 2007 / Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia / Di
Cani PD / 2008 / Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice / Diabetes 57 : 1470 ~ 14
Dourmashkin JT / 2005 / Different forms of obesity as a function of diet composition / Int J Obes (Lond) 29 : 1368 ~ 1378
Backhed F / 2004 / The gut microbiota as an environmental factor that regulates fat storage / Proc Natl Acad Sci U S A 101 : 15718 ~ 15723
Cani PD / 2007 / Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia / Di
Cani PD / 2008 / Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice / Diabetes 57 : 1470 ~ 14
Dourmashkin JT / 2005 / Different forms of obesity as a function of diet composition / Int J Obes (Lond) 29 : 1368 ~ 1378
이 논문의 저자 정보
최근 본 자료
댓글(0)
0