지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 75 - 80 (6page)
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초록· 키워드
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Background: White blood cell count is an independent risk factor for cardiovascular disease. Several lifestyle and metabolic factors such as cigarette smoking and obesity are known to be associated with an elevated white blood cell count. However, the joint effect of cigarette smoking and obesity on white blood cell count has not yet been fully described.Methods: We explored the joint effect of cigarette smoking and obesity on white blood cell count using multiple lo-gistic regression analyses after adjusting for confounding variables in a population-based, cross-sectional study of 416,065 Korean adults.Results: Cigarette smoking and body mass index have a dose-response relationship with a higher white blood cell count, but no synergistic interaction is observed between them (men, P for interaction=0.797; women, P for inter-action=0.311). Cigarette smoking and body mass index might have an additive combination effect on high white blood cell count. Obese male smokers were 2.36 times more likely and obese female smokers 2.35 times more likely to have a high white blood cell count when compared with normal body mass index non-smokers.Conclusion: Cigarette smoking and body mass index are independently associated with an elevated white blood cell count in both men and women.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Syvanne M / 1997 / Lipids and lipoproteins as coronary risk factors in non-insulin-dependent diabetes mellitus / Lancet 350(Suppl 1):S20~S23
Boden G / 2003 / Effects of free fatty acids on gluconeogenesis and glycogenolysis / Life Sci 72:977~988
Staehr P / 2003 / Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis / Diabetes 52:260~267
Jee SH / 2005 / White blood cell count and risk for all-cause, cardiovascular, and cancer mortality in a cohort of Koreans / Am J Epidemiol 162:1062~1069
Lee CD / 2001 / White blood cell count and incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women : atherosclerosis risk in communities study / Am J Epidemiol 154:758~764
Boden G / 2003 / Effects of free fatty acids on gluconeogenesis and glycogenolysis / Life Sci 72:977~988
Staehr P / 2003 / Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis / Diabetes 52:260~267
Jee SH / 2005 / White blood cell count and risk for all-cause, cardiovascular, and cancer mortality in a cohort of Koreans / Am J Epidemiol 162:1062~1069
Lee CD / 2001 / White blood cell count and incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women : atherosclerosis risk in communities study / Am J Epidemiol 154:758~764
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