지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 292 - 298 (7page)
이용수
초록· 키워드
오류제보하기
Background: Mucormycosis is an uncommon and life-threatening fungal infection. The clinical predictors of outcome were evaluated in patients with invasive mucormycosis.
Materials and Methods: We retrospectively reviewed histologically proven cases of invasive mucormycosis in our institution from 1996 to 2012.
Results: A total of 64 patients were analyzed. The median age was 59 years (interquartile range [IQR], 50–67), and 32 patients (50%)were male. The most common underlying diseases were diabetes mellitus (67%), hematologic malignancy (22%), and solid cancer (19%). The most common infection sites were the rhino-orbito-cerebral area (56%) and the lungs (31%). The 180-day all-cause mortality was 33%. Disseminated infection was associated with increased mortality (hazard ratio [HR]: 169.74, 95% confidence interval [CI]: 6.41 to 4492.64; P = 0.002). Pulmonary infection (HR: 0.08, 95% CI: 0.01 to 0.66; P = 0.02) and complete surgical removal of infected tissue (HR: 0.12, 95% CI: 0.02 to 0.64; P = 0.01) were associated with decreased mortality.
Conclusions: These results suggest that patients with mucormycosis had a lower risk of mortality if they developed a pulmonary infection, rather than a disseminated infection and with complete debridement of infected tissue.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Bitar D / 2009 / Increasing incidenceof zygomycosis (mucormycosis), France, 1997-2006 / Emerg Infect Dis 15 : 1395 ~ 1401
Boelaert JR / 1993 / Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animalstudies / J Clin Invest 91 : 1979 ~ 1986
Cinque P / 1997 / Varicella-zoster virus (VZV) DNAin cerebrospinal fluid of patients infected with human immunodeficiencyvirus: VZV disease of the central nervoussystem or s
De Pauw B / 2008 / European Organizationfor Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group; National Institute of Allergyand Infectious Disease
Frater JL / 2001 / Histologic features of zygomycosis:emphasis on perineural invasion and fungalmorphology / Arch Pathol Lab Med 125 : 375 ~ 378
Boelaert JR / 1993 / Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animalstudies / J Clin Invest 91 : 1979 ~ 1986
Cinque P / 1997 / Varicella-zoster virus (VZV) DNAin cerebrospinal fluid of patients infected with human immunodeficiencyvirus: VZV disease of the central nervoussystem or s
De Pauw B / 2008 / European Organizationfor Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group; National Institute of Allergyand Infectious Disease
Frater JL / 2001 / Histologic features of zygomycosis:emphasis on perineural invasion and fungalmorphology / Arch Pathol Lab Med 125 : 375 ~ 378
이 논문의 저자 정보
최근 본 자료
댓글(0)
0