지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 191 - 195 (5page)
이용수
초록· 키워드
오류제보하기
Oleanolic acid is a natural triterpenoid that exists widely in foods and some medicinal herbs. The purpose of this study was to determine the antimicrobial activity of oleanolic acid against Streptococcus mutans strains isolated from a Korean population. Antimicrobial activity against these bacteria was evaluated by minimal inhibitory concentration (MIC) and time kill curves. The tolerance of human gingival fibroblasts and human periodontal ligaments to oleanolic acid was tested using a methyl thiazolyl tetrazolium (MTT) assay. The MIC90 value of oleanolic acid for both S. mutans and S.
sobrinus isolated from Koreans was 8 μg/ml. Oleanolic acid showed bactericidal effects against S. mutans ATCC 25175Tand S. sobrinus ATCC 33478Tat 1 × MIC (8 μg/ml) and had no cytotoxic effects against KB cells at this dose. The results suggest that oleanolic acid could be useful in the future development of oral hygiene products for the prevention of dental caries.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Asmussen, E / 1984 / Softening of BISGMA-based polymers by ethanol and by organic acids of plaque / Scand J Dent Res 92 : 257 ~ 261
Fontanay S / 2008 / Ursolic,oleanolic and betulinic acids: Antibacterial spectra and selectivity indexes / J Ethnopharmacol 120 : 272 ~ 276
Horiuchi K / 2007 / Antimicrobial activity of oleanolic acid from Salvia officinalis and related compounds on vancomycin-resistant enterococci (VRE) / Biol Pharm Bull 30 : 11
Kahkonen MP / 1999 / Antioxidant activity of plant extracts containing phenolic compounds / J Agric Food Chem 47 : 3954 ~ 3962
Kim DO / 2003 / Quantification of polyphenolics and their antioxidant capacity in fresh plums / J Agri Food Chem 51 : 6509 ~ 6515
Fontanay S / 2008 / Ursolic,oleanolic and betulinic acids: Antibacterial spectra and selectivity indexes / J Ethnopharmacol 120 : 272 ~ 276
Horiuchi K / 2007 / Antimicrobial activity of oleanolic acid from Salvia officinalis and related compounds on vancomycin-resistant enterococci (VRE) / Biol Pharm Bull 30 : 11
Kahkonen MP / 1999 / Antioxidant activity of plant extracts containing phenolic compounds / J Agric Food Chem 47 : 3954 ~ 3962
Kim DO / 2003 / Quantification of polyphenolics and their antioxidant capacity in fresh plums / J Agri Food Chem 51 : 6509 ~ 6515
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Oleanolic acid의 Streptococcus mutans 및 S. sobrinus에 대한 항균효과
대한치과재료학회 학술대회
2008 .11
-
Antimicrobial Effects of Ursolic Acid against Mutans Streptococci Isolated from Koreans
International Journal of Oral Biology
2011 .01
-
Oleanolic acid 3-acetate, a minor element of ginsenosides, induces apoptotic cell death in ovarian carcinoma and endometrial carcinoma cells via the involvement of a reactive oxygen species-independent mitochondrial pathway
Journal of Ginseng Research
2020 .01
-
Oleanolic Acid, a Pentacyclic Triterpenoid, Induces Rabbit Platelet Aggregation through a Phospholipase C-Calcium Dependent Signaling Pathway
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Oleanolic acid 및 Ursolic Acid의 Streptococcus downei에 대한 항균작용
치위생과학회지
2011 .01
-
6세 이하의 어린이에서 Streptococcus mutans와 Streptococcus sobrinus의 분포에 관한 연구
대한소아치과학회지
2005 .01
-
The therapeutic effect of oleanolic acid acetate on experimental autoimmune encephalomyelitis
한국실험동물학회 학술발표대회 논문집
2016 .08
-
Isolation and Characterization of the Streptococcus mutans from Korean Children with Caries
대한의생명과학회지
2007 .12
-
혼합치열기 어린이에서 Streptococcus mutans와 Streptococcus sobrinus의 분포도 조사
대한소아치과학회지
2007 .01
-
소아의 치면세균막에 존재하는 mutans streptococci의 분포
대한소아치과학회지
2004 .01
-
The inhibitory effect of Oleanolic acid acetate on osteoclast differentiation and suppresses bone loss in mice
대한체질인류학회 학술대회 연제 초록
2013 .05
-
치면세균막에서 분리한 뮤탄스 연쇄상구균 및 Streptococcus anginosus의 수종 항생제에 대한 감수성 조사
Restorative Dentistry and Endodontics
2004 .01
-
산에대한Streptococcus mutans KCTC 3065의스트레스반응에관한연구
치위생과학회지
2007 .01
-
Regulation of proinflammatory cytokines gene expression by oleanolic acid in mouse peritoneal Macrophages
대한약학회 학술대회
2000 .01
-
Isolation of epi-Oleanolic Acid from Korean Mistletoe and Its Apoptosis-Inducing Activity in Tumor Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Realtime PCR법에 의한 청소년의 치아우식 유발세균 감염률 조사
대한구강보건학회지
2020 .01
-
단일클론항체를 사용한 타액 내 Streptococcus mutans 검출
대한소아치과학회지
2015 .01
-
Apoptosis-inducing avtivity of epi-oleanolic acid isolated from Korean Mistletoe
한국실험동물학회 학술발표대회 논문집
2002 .06
-
Antimicrobial Effects of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Enterococcus faecalis and Propionibacterium acnes
International Journal of Oral Biology
2014 .01
-
Cytotoxic Constituents of Pilea mongolica
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1997 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0