지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 99 - 106 (8page)
이용수
초록· 키워드
오류제보하기
Type1 diabetes mellitus (DM) is generally known to be caused by destruction of insulin-producing pancreatic β cells or an immune-related problem. Polydipsia is a representative symptom of DM, and it has been reported that this condition is closely related to xerostomia and is considered that hyposalivation from the salivary gland results in this phenomenon. Although various studies have reported that induction of diabetes reduces endogenous stem cells in other organs (heart, brain etc.), diabetes-related changes in endogenous stem cells in the salivary gland have not yet been well established. Therefore, in this study, to verify the change in salivary gland stem cells after diabetes, salivary gland tissues in the control and diabetes-induced groups were processed by histochemistry (Masson’s trichrome staining) for morphological analysis, TUNEL assay for cell death, and immunohistochemistry (Ki-67 and c-Kit) for cell proliferation and maturation. Diabetes induced by STZ leads to vacuolization, apoptosis, and reduction in proliferating cells/salivary gland stem cells in salivary glands of rats. This result suggests that diabetes may be associated with reduction in salivary gland function such as degeneration and inhibition of regeneration in the salivary gland.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Ashleigh S. Boyd / 2012 / Concise Review: Immune Recognition of Induced Pluripotent Stem Cells / STEM CELLS 30 (5) : 797 ~ 803
Atsushi Suzuki / 2002 / Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver / The Journal of Cell Biology 156 (1) : 17
Catherine Andre / 1997 / Sequence Analysis of Two Genomic Regions Containing the KIT and the FMS Receptor Tyrosine Kinase Genes / Genomics 39 (2) : 216 ~ 226
Charlotte E. Edling / 2007 / c-Kit?A hematopoietic cell essential receptor tyrosine kinase / The International Journal of Biochemistry & Cell Biology 39 (11) : 1995 ~ 19
Christopher A. Sullivan / 2005 / Chemoradiation-Induced Cell Loss in Human Submandibular Glands / The Laryngoscope 115 (6) : 958 ~ 964
Atsushi Suzuki / 2002 / Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver / The Journal of Cell Biology 156 (1) : 17
Catherine Andre / 1997 / Sequence Analysis of Two Genomic Regions Containing the KIT and the FMS Receptor Tyrosine Kinase Genes / Genomics 39 (2) : 216 ~ 226
Charlotte E. Edling / 2007 / c-Kit?A hematopoietic cell essential receptor tyrosine kinase / The International Journal of Biochemistry & Cell Biology 39 (11) : 1995 ~ 19
Christopher A. Sullivan / 2005 / Chemoradiation-Induced Cell Loss in Human Submandibular Glands / The Laryngoscope 115 (6) : 958 ~ 964
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
In vitro stem cell differentiation for salivary gland regeneration: a comprehensive review
MEDICAL LASERS
2024 .03
-
Application of Developmental Principles for Functional Regeneration of Salivary Glands
해부·생물인류학
2019 .09
-
Optimal Treatment for the High-Risk Salivary Gland Cancer
Clinical and Experimental Otorhinolaryngology
2020 .01
-
Effect of Gamma Irradiation on the Function of Mouse Salivary Glands
한국실험동물학회 학술발표대회 논문집
2016 .02
-
Preventive effect of polydatin on diabetes related hypofunction of salivary gland in streptozotocin-induced diabetic rats
Journal of Biomedical and Translational Research
2021 .12
-
Metachronous malignant tumors in ipsilateral salivary glands
Archives of craniofacial surgery : ACFS
2019 .01
-
Assessment of Age-Related Dimensions of the Salivary and Thyroid Glands Using Three-Dimensional Computed Tomography in Children
대한이비인후-두경부외과학회지
2016 .01
-
Salivary Gland Hyalinizing Clear Cell Carcinoma
Journal of Pathology and Translational Medicine
2015 .01
-
웃음치료를 통한 침샘자극이 허약노인의 구강건조와 타액 pH에 미치는 효과
지역사회간호학회지
2016 .03
-
Changes in Protein Phosphorylation during Salivary Gland Degeneration in Haemaphysalis longicornis
Parasites, Hosts and Diseases
2020 .04
-
Primary squamous cell carcinoma of the salivary gland: immunohistochemical analysis and comparison with metastatic squamous cell carcinoma
Journal of Pathology and Translational Medicine
2020 .01
-
Role of Homeostatic Changes in Salivary Gland Acinar Cells in Primary Sjögren"s Syndrome: A Review
Journal of Oral Medicine and Pain
2023 .06
-
P.gingivalis LPS-induced inflammation lead to degeneration in salivary glands of mice
한국실험동물학회 학술발표대회 논문집
2020 .02
-
Characterization of mouse salivary gland organoid; spheroid expansion, organoid maturation and disease modeling
한국실험동물학회 학술발표대회 논문집
2020 .07
-
A retrospective cytohistological correlation of fine-needle aspiration cytology with classification by the Milan System for Reporting Salivary Gland Cytopathology
Journal of Pathology and Translational Medicine
2020 .01
-
Toothache Caused by Sialolithiasis of the Submandibular Gland
Journal of Oral Medicine and Pain
2018 .09
-
Autoantibody-Mediated Dysfunction of Salivary Glands Leads to Xerostomia in SKG Mice
Immune Network
2019 .12
-
Rabbit submandibular salivary gland replantation
대한구강악안면외과학회지
2017 .01
-
Salivary Flow According to Elderly"s Whole Health and Oral Health Status: According to Application of Oral exercise and Salivary Gland Massage
대한의생명과학회지
2019 .09
-
구강 내 소타액선에 발생한 점액표피양 암종 1예
대한 두경부 종양 학술지
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0