지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제47권 제2호
- 발행연도
- 2013.1
- 수록면
- 93 - 99 (7page)
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초록· 키워드
오류제보하기
Acinar cell carcinoma is a rare malignant epithelial neoplasm with predominantly exocrine acinar differentiation and is seen primarily in older men (mean age, 62 years). The presenting symptoms are usually non-specific, and jaundice is often not present. Symptoms relating to the overproduction and release of lipase into the circulation are present in 10-15% of patients. Characteristic cytomorphologic features include a population of cells with minimal pleomorphism, eccentrically placed nuclei with a single prominent nucleoli and moderate hyperchromasia. The cytoplasm is finely granular, and the background may contain granular debris secondary to cytolysis. A significant proportion of the cases also have a minor neuroendocrine component or scattered neuroendocrine cells. Approximately 50% of patients have metastatic disease at presentation, often restricted to the regional lymph nodes and liver. The prognosis is poor, only slightly better than that of pancreatic ductal adenocarcinoma.
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참고문헌 (25)
참고문헌 신청
Agaimy A / 2011 / Pancreatic-type acinar cell carcinoma of the liver: a clinicopathologic study of four patients / Mod Pathol 24 : 1620 ~ 1626
Albores-Saavedra J / 2002 / Acinar cystadenoma of the pancreas: a previously undescribed tumor / Ann Diagn Pathol 6 : 113 ~ 115
Ambrosini-Spaltro A / 2009 / Pancreatictype acinar cell carcinoma of the stomach beneath a focus of pancreatic metaplasia of the gastric mucosa / Hum Pathol 40 : 746 ~ 749
Burns WA / 1974 / Lipase-secreting acinar cell carcinoma of the pancreas with polyarthropathy: a light and electron microscopic, histochemical, and biochemical study / Cance
Chatelain D / 2002 / Unilocular acinar cell cystadenoma of the pancreas an unusual acinar cell tumor / Am J Clin Pathol 118 : 211 ~ 214
Albores-Saavedra J / 2002 / Acinar cystadenoma of the pancreas: a previously undescribed tumor / Ann Diagn Pathol 6 : 113 ~ 115
Ambrosini-Spaltro A / 2009 / Pancreatictype acinar cell carcinoma of the stomach beneath a focus of pancreatic metaplasia of the gastric mucosa / Hum Pathol 40 : 746 ~ 749
Burns WA / 1974 / Lipase-secreting acinar cell carcinoma of the pancreas with polyarthropathy: a light and electron microscopic, histochemical, and biochemical study / Cance
Chatelain D / 2002 / Unilocular acinar cell cystadenoma of the pancreas an unusual acinar cell tumor / Am J Clin Pathol 118 : 211 ~ 214
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