지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제2권 제5호
- 발행연도
- 2014.1
- 수록면
- 387 - 390 (4page)
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초록· 키워드
오류제보하기
Cudrania tricuspidata is a deciduous tree belonging to the Moraceae plant, which has been widely used as a folk remedy or health supplements in the Asian countries including Korea. As far as we know, side effects from taking the extract of C. tricuspidata has not yet been reported. We reviewed the electronic medical records of 2 patients who had adverse drug reactions to C. tricuspidata. The first case was a 30-year-old woman without a specific medical history. She was admitted with a 2-week history of jaundice and dyspepsia after taking extract of C. tricuspidata for 3 days. Initial laboratory findings were as follows: aspartate aminotransferase, 364 IU/L; alanine aminotransferase, 574 IU/L; total bilirubin, 36.3 mg/dL; and direct bilirubin, 18.3 mg/dL. She was conservatively treated for liver and renal failure while awaiting liver transplantation. However, she was expired due to combined pneumonia and progressed hepatic and renal failure. The second case was a 42-year-old woman who has chronic urticaria without other medical history. She was admitted with a 3-month history of whole body rash with small pustular vesicle after taking extract of C. tricuspidata. She was treated with intravenous steroids and antihistamines. Skin lesions were improved after 1 week. Here, we report 2 cases of adverse drug reaction to C. tricuspidata. It should be considered that C. tricuspidata ingestion could cause severe adverse drug reactions such as liver failure and acute generalized exanthematous pustulosis.
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등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Ahn BM / 2004 / Herbal preparation-induced liver injury / Korean J Gastroenterol 44 : 113 ~ 125
An RB / 2006 / Hepatoprotective compounds of the roots of Cudrania tricuspidata on tacrine-induced cytotoxicity in Hep G2 cells / Biol Pharm Bull 29 : 838 ~ 840
Bent S / 2004 / Commonly used herbal medicines in the United States: a review / Am J Med 116 : 478 ~ 485
Britschgi M / 2001 / T-cell involvement in drug-induced acute generalized exanthematous pustulosis / J Clin Invest 107 : 1433 ~ 1441
Chang SL / 2008 / Clinical manifestations and characteristics of patients with acute generalized exanthematous pustulosis in Asia / Acta Derm Venereol 88 : 363 ~ 365
An RB / 2006 / Hepatoprotective compounds of the roots of Cudrania tricuspidata on tacrine-induced cytotoxicity in Hep G2 cells / Biol Pharm Bull 29 : 838 ~ 840
Bent S / 2004 / Commonly used herbal medicines in the United States: a review / Am J Med 116 : 478 ~ 485
Britschgi M / 2001 / T-cell involvement in drug-induced acute generalized exanthematous pustulosis / J Clin Invest 107 : 1433 ~ 1441
Chang SL / 2008 / Clinical manifestations and characteristics of patients with acute generalized exanthematous pustulosis in Asia / Acta Derm Venereol 88 : 363 ~ 365
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