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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제5호
- 발행연도
- 2015.1
- 수록면
- 313 - 319 (7page)
이용수
초록· 키워드
오류제보하기
There has been growing concern regarding the effects of ambient air pollution on asthma. Particulate matter (PM) is one of the major air pollutants affecting both general population and the patients with asthma. This paper reviews the recent evidence of the adverse effects of PM on the inception and morbidity of asthma. Epidemiological studies confirmed that short-term exposure to PM aggravated respiratory symptoms and lung function in asthma patients. Furthermore, PM induces acute exacerbations of asthma with increased risk of hospitalization and death. Long-term exposure to PM is responsible for new onset of asthma and lung function decline in both children and adults. Various mechanisms are involved in the effects of PM on airway including oxidative stress, augmentation of inflammation, promotion of allergen sensitization, induction of airway hyperresponsiveness, aggravation of rhinitis and DNA methylation. Special attention and care is needed for the patients with asthma to prevent the detrimental effects of PM.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Ahmed E / 2015 / Long-term trend of airborne particulate matter in Seoul, Korea from 2004 to 2013 / Atmos Environ 101 : 125 ~ 133
Asgharian B / 2014 / Computational modeling of nanoscale and microscale particle deposition, retention and dosimetry in the mouse respiratory tract / Inhal Toxicol 26 : 829 ~
Brook RD / 2010 / Particulate matter air pollution and cardiovascular disease : an update to the scientific statement from the American Heart Association / Circulation 121 :
Delamater PL / 2012 / An analysis of asthma hospitalizations, air pollution, and weather conditions in Los Angeles County, California / Sci Total Environ 425 : 110 ~ 118
Eder W / 2006 / The asthma epidemic / N Engl J Med 355 : 2226 ~ 2235
Asgharian B / 2014 / Computational modeling of nanoscale and microscale particle deposition, retention and dosimetry in the mouse respiratory tract / Inhal Toxicol 26 : 829 ~
Brook RD / 2010 / Particulate matter air pollution and cardiovascular disease : an update to the scientific statement from the American Heart Association / Circulation 121 :
Delamater PL / 2012 / An analysis of asthma hospitalizations, air pollution, and weather conditions in Los Angeles County, California / Sci Total Environ 425 : 110 ~ 118
Eder W / 2006 / The asthma epidemic / N Engl J Med 355 : 2226 ~ 2235
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